Ge Healthcare Bio-sciences Ab

Amersham Pharmacia Biotech Ab

Cytiva Sweden Ab

Stig Tormod

Patrik Berndt Akerstrom

Mikael Hornqvist

Hakan Frojdh

Owe Salven

Håkan Fröjdh

Mikael HÖRNQVIST

Patrik ÅKERSTRÖM

The present invention discloses a flow cell optical detection system comprising a light source, a flow cell and a light detector, wherein the light detector is arranged in a separate detector unit that is arranged to be releasably attached to a detector interface, the detector interface being in optical communication with the light source and comprises optical connectors for optically connecting the flow cell and the detector unit in the light path from the light source, and wherein the flow cell is an interchangeable unit arranged to be held in position by the detector unit when attached to the detector interface.

Flow cell optical detection system

An adjustable holder () for a concave holographic grating () for enabling the correct positioning of the grating vis-&#xe0;-vis a light entrance port () and a light exit port (), characterized in, that it comprises a grating hinge () fixed to said grating, said grating hinge () enabling rotational adjustment of the grating position with respect to said holder (), the center point of the rotational adjustment being located at the vertex of said grating ().

Holder for a holographic grating

Optical flow cell detector comprising a sample inlet and outlet in fluidic communication through a flow cell channel of cross sectional area A, an input light guide with an light exit surface arranged adjacent and in optical alignment with a light entrance surface of an output light guide, wherein the input light guide and the output light guide protrudes into the flow cell channel and wherein the distance between the light exit surface and the light entrance surface is less than 1.0 mm, and wherein the cross sectional area of the protruding portions of the input light guide and the output light guide in the flow direction is less than A/2.

Optical flow cell detector

The present invention relates to methods and apparatus for detecting and measuring the concentration of a substance in a solution, the substance having an absorption at 300 nm or less. The methods and apparatus have particular utility in detecting and measuring the concentration of proteins and nucleic acids.

Methods and apparatus for measuring the concentration of a substance in a solution

Multiplexer for electromagnetic radiation, e.g. UV-light, in which a single electromagnetic radiation source () and a single electromagnetic radiation detector () are connectable in turn to a plurality of sample-containing units (()-()). The multiplexer comprises a sled () movable in relation to a fixed base () by an actuator ().

Optical multiplexer for liquid samples in a conduit

The invention relates to a method of calibrating an optical system, the system comprising a flash lamp as a light source (,), a lens system (,), a monochromator comprising a grating (,), a motor (,) for displacing the grating so as to enable scanning essentially monochromatic light over a detection system. The light source provides at least two high intensity peaks at distinct wavelengths. The method comprises scanning a first wavelength region comprising at least one of said at least two high intensity peaks, and measuring the intensities at a selected number of points during the scan. A first of said at least two peaks is coarsely located. A wavelength region around each of said at least two peaks is scanned, measuring the intensities at closer intervals than previously. At least two peaks are located by autocorrelation. The location of said peaks is determined in terms of a distance from a reference point, said distance corresponding to said displacement of the grating.

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Uppsala, Sweden

Stig Tormod