The University of New Mexico

Other

Steven Wayde Graves

Gabriel P Lopez

Darko Stefanovic

Menake E Piyasena

Andrew P Shreve

Carl Brown, Iii

Matthew Richard Lakin

Robert W Applegate, Jr

Bruce S Edwards

Daniel Kalb

Alireza Goudarzi

Pearlson Prashanth Austin Suthanthiraraj

Jaime Javier Juarez

The invention is directed to a hybrid architecture that comprises a stacked autoencoder and a deep echo state layer for temporal pattern discovery in high-dimensional sequence data. The stacked autoencoder plays a preprocessing role that exploits spatial structure in data and creates a compact representation. The compact representation is then fed to the echo state layer in order to generate a short-term memory of the inputs. The output of the network may be trained to generate any target output.

Hybrid architecture system and method for high-dimensional sequence processing

A method to simultaneously detect emission intensity or images at multiple distinct emission wavelengths in the analysis of parallel sample streams in a flow-based analysis system and apparatus for performing the described method.

Method for simultaneous spectrally resolved detection or imaging of items in multiple flowing streams

This disclosure describes a structured polynucleotide, devices that include the structured polynucleotide, and methods involving the structured polynucleotide and/or devices. Generally, the structured polynucleotide includes five domains. A first domain acts as a toehold for an input DNA logic gate to initiate binding to an SCS biomolecule. A second domain acts as a substrate recognition sequence for an upstream DNA logic gate. A third domain acts as a toehold for a output DNA logic gate to initiate binding of the SCS biomolecule to the gate. A fourth domain acts as an effector sequence to alter the state of the output logic gate. A fifth domain acts as a cage sequence to lock the effector sequence in an inactive state until an input gate binds to the structured polynucleotide.

Signal propagation biomolecules, devices and methods

An affordable flow cytometry system with a significantly increased analytical rate, volumetric sample delivery and usable particle size including a light beam that interrogates multiple flow streams so as to provide excitation across all of the streams, and an optical objective configured to collect light from the sample streams and image the light onto an array detector.

Spatially correlated light collection from multiple sample streams excited with a line focused light source

An analytical device such as a flow cytometer is provided in which a fluid sample flowing through a channel is focused into multiple, parallel particle streams by an acoustic wave field extending across the channel. Each stream is then presented to an individual detector to allow for simultaneous interrogation of the multiple streams and thus, high-throughput analysis of the fluid sample.

Multinode acoustic focusing for parallel flow cytometry analysis applications

Growing community of inventors

Santa Fe, NM, United States of America

Steven Wayde Graves