Abbott Laboratories Corporation

Steven W Muchmore

Hing L Sham

Dale J Kempf

Chen Zhao

Gary T Wang

Allan C Krueger

Clarence J Maring

Kent D Stewart

Ming Clinton Yeung

Warren M Kati

Minghua Sun

Vincent L Giranda

David J Grampovnik

Yuanwei Chen

Darold L Madigan

Vincent S Stoll

Yu Gui Gu

Sheldon Wang

David A Degoey

Zhen Lin

April Kennedy

Larry L Klein

Keith F McDaniel

Stephen Hanessian

Paul E Wiedeman

Hui-Ju J Chen

Jonathan Greer

Jeffrey Y Pan

William J Flosi

Xuehong Luo

Ronald B Jones

Yibo Xu

Jeffrey A Olson

Vicki L Nienaber

Frank L Wagenaar

Noah P Tu

Malken Bayrakdarian

Inhibitors of neuraminidases

Method for mounting a sample comprising a crystal for X-ray crystallographic analysis, a method for aligning a sample comprising a crystal for X-ray crystallographic analysis, which sample is mounted on a positioning device, and a method for determining the structure of a sample containing a crystal by means of X-ray crystallography. The method includes activating a robot so that the tool retrieves the crystal holder, receives a sufficient amount of a fluid to maintain the crystal in the crystal holder at a temperature not in excess of about 160 degrees K, transfers the retrieved crystal holder to a positioning device, and mounts the transferred crystal holder on the positioning device, whereby the crystal in the retrieved crystal holder is maintained at a temperature not in excess of about 160 degrees K.

Automated sample handling for X-ray crystallography

Five-membered carbocyclic and heterocyclic inhibitors of neuraminidases

Method and apparatus for mounting a sample comprising a crystal for X-ray crystallographic analysis, a method for aligning a sample comprising a crystal for X-ray crystallographic analysis, which sample is mounted on a positioning device, and a method for determining the structure of a sample containing a crystal by means of X-ray crystallography.

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Libertyville, IL, United States of America

Steven W Muchmore