Life Technologies Corporation

Biometric Imaging, Inc.

Arcturus Engineering, Inc.

Mds Analytical Technologies (us) Inc.

Steven T Kunitake

Derrick A Richardson

Derek Pai

Jorge Monteon

Bala S Manian

David F Head

Robert H Reamey

Thomas L Smith

Ann Bennett Lossing

Sherrie L Ransom

Hala Al-Shawany

Kurt R Jarnagin

Derek S Pai

This relates to filter columns for isolating nucleic acids, particularly at small elution volumes. The filter column is adapted for stable placement within the upper portion of standard plastic collection tubes of various sizes. The body of the filter column has a number of surfaces to accommodate placement within variously sized collection tubes. The filter column contains nucleic acid-specific filter which can be located at alternate regions within the filter column, providing different filter surface areas and loading volume capacities using the same column body. The filter column has an opening on an upper end adapted to be sealed by a cap. A method for recovering nucleic acids using such filter column is also provided.

Low volume filtration column devices and methods of filtering therewith

Systems and methods are described for barriers on laser capture microdissection samples. A method of processing a biological sample for laser capture microdissection, includes: providing the biological sample; and applying a substance to the biological sample so as to provide a barrier between the biological sample and a surrounding environment. The systems and methods provide advantages because non-specific pick-up is reduced, visualization is improved, sample degradation is reduced, and contamination is reduced.

Processing technology for LCM samples

An apparatus and method of use for assaying cellular motility in response to a concentration gradient of a chemotactic agent. Generally, the apparatus includes a chamber having a region for receiving a biological sample containing cells of interest and, spaced apart from such region, another region for receiving a chemotactic agent. Between these regions, a concentration gradient of chemotactic agent is established. The apparatus further includes an optical system for detecting and mapping the positions of individual cells responsive to such concentration gradient. Means for processing and analyzing the collected data are also provided. Motility determinations may be made on purified or unpurified samples. Single-site assay devices and multi-site, high-throughput assay devices are disclosed.

Cell motility assay

Growing community of inventors

San Carlos, CA, United States of America

Steven T Kunitake