Societe Des Produits Nestle S.a.

Nestec S.a.

Ralston Purina Company

Steven Scott Hannah

Rondo Paul Middleton

Serge Andre Dominique Rezzi

Brian Michael Zanghi

Qinghong Li

Dorothy P Laflamme

Scott Sherrill

Peichuan Sun

Robert M Stuckey

Lawrence McDaniel, Iii

Ebenezer Satyaraj

Alison Beloshapka

Christina Petzinger Germain

James Kaput

Yuanlong Pan

Mark K Waldron

Brian M Zanghi

Gail Czarnecki-Maulden

Rondo P Middleton

Marie Pier Scott-Boyer

Nikola Djordjevic

Sebastien Lacroix

Serge Andre Rezzi

Nikola Dordevic

A pet food composition contains protein, carbohydrates, fat, fiber, and at least 6 distinct metabolites. The at least 6 distinct metabolites include first and second metabolites for modulating bone mineral content, third and fourth metabolites for modulating 25(OH) vitamin D3, and fifth and sixth metabolites for modulating 1,25(OH)vitamin D3 in a companion animal.

Pet food compositions that modulate vitamin D and bone mineral content in a companion animal

A pet food composition specifically formulated for a small dog can include a combination of specific amino acids and probiotics to maintain or increase absorption of amino acids. Methods of increasing absorption of amino acids are also provided.

Compositions and methods for small canines

A specific type of organ health marker in a companion animal can be improved by adjusting the diet of the animal to increase the amount of a compound which positively or negatively modulates the specific type of organ health marker or adjusting the diet of the animal to decrease the amount of a compound which positively or negatively modulates the specific type of organ health marker. The specific type of organ health marker can be one or more of phosphorus, alkaline phosphatase, aspartate aminotransferase, or gamma-glutamyltransferase.

Compositions and methods that modulate phosphorus or enzymes in a companion animal

The present disclosure provides methods for enabling an individual having a cat allergy to have a cat as a pet. Such a method can include quantitatively determining a threshold in the individual for an environmental level of an allergen produced by the cat and selecting a cat or a breed of cat that creates an environmental level of the allergen that is less than the threshold. Additionally, such a method can include lowering the allergens disseminated by the cat by treating the environment inhabited by the cat during a time period where the cat expresses elevated allergens.

Methods for enabling pet ownership

Bone mineral content, 25(OH) vitamin D3, or 1,25(OH)vitamin D3 in a companion animal can be improved by adjusting the diet of the animal to increase the amount of a compound which positively or negatively modulates the bone mineral content, 25(OH) vitamin D3, or 1,25(OH)vitamin D3 or adjusting the diet of the animal to decrease the amount of a compound which positively or negatively modulates the bone mineral content, 25(OH) vitamin D3, or 1,25(OH)vitamin D3.

Compositions and methods that modulate vitamin D and bone mineral content in a companion animal

White blood cells and/or neutrophils in a companion animal can be improved by adjusting the diet of the animal to increase the amount of a compound which positively or negatively modulates the white blood cells and/or neutrophils or adjusting the diet of the animal to decrease the amount of a compound which positively or negatively modulates the white blood cells and/or neutrophils.

Compositions and methods that modulate white blood cells or neutrophils in a companion animal

Cholesterol, high-density lipoproteins, and low-density lipoproteins in a companion animal can be improved by adjusting the diet of the animal to increase the amount of a compound which positively or negatively modulates the cholesterol, high-density lipoproteins, or low-density lipoproteins or adjusting the diet of the animal to decrease the amount of a compound which positively or negatively modulates cholesterol, high-density lipoproteins, or low-density lipoproteins.

Compositions and methods that modulate cholesterol in a companion animal

A specific bacterium in a companion animal can be improved by adjusting the diet of the animal to increase the amount of a compound which positively or negatively modulates the specific type of bacterium or to decrease the amount of a compound which positively or negatively modulates the specific type of bacterium. The specific type of bacterium can be one or more of, or

Compositions and methods that modulate bacteria in a companion animal

A specific type of digestibility in a companion animal can be improved by adjusting the diet of the animal to increase the amount of a compound which positively or negatively modulates the specific type of digestibility or adjusting the diet of the animal to decrease the amount of a compound which positively or negatively modulates the specific type of digestibility. The specific type of digestibility can be one or more of organic matter digestibility, dry matter digestibility, fiber digestibility, energy digestibility, fat digestibility, or protein digestibility.

Compositions and methods that modulate digestibility in a companion animal

A pet food composition specifically formulated for a small dog can include a combination of specific antioxidants, amino acids, metabolism components, and bone health components to maintain health. Methods of maintaining health and modulating select health parameters are also provided.

The invention provides methods for diagnosing degenerative joint disease in an animal by collecting a saliva sample from an animal; determining the amount of at least one diagnostic agent selected from the group consisting of interferon gamma, interferoninducible protein-10, interleukin-2, and total saliva protein in the saliva sample; comparing the amount of diagnostic agent found in the saliva sample to a corresponding amount of the same diagnostic agent found in a saliva sample from one or more comparable control animals that do not suffer from degenerative joint disease; and diagnosing that the animal is susceptible to or suffering from degenerative joint disease if the amount of diagnostic agent in the saliva sample from the animal is greater than the amount of same diagnostic agent found in the saliva sample from the one or more comparable control animals.

Methods for diagnosing degenerative joint disease

The invention provides methods, compositions, and dietary formulations useful for preventing or treating dermatitis, promoting healthy skin, and retarding skin aging. The methods comprise administering to an animal a therapeutically effective amount of a combination of at least two of one or more antioxidants; one or more anti-glycation agents; one or more body fat reducing agents; one or more insulin sensitivity enhancing agents; and one or more anti-inflammatory agents.

Methods and compositions suitable for promoting healthy skin

Dietary formulations and methods for treating, preventing or delay onset of osteoarthritis in canines and other animals are disclosed. The formulations are enriched in n-3 fatty acids and limited in n-6 fatty acids.

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Chesterfield, MO, United States of America

Steven Scott Hannah