Shaman Pharmaceuticals, Inc.

Napo Pharmaceuticals, Inc.

Salix Pharmaceuticals, Inc.

Steven Row King

Jian Luo

William Forbes

Enoch Bortey

Donald E Bierer

Pravin R Chaturvedi

Reimar C Bruening

Jeffrey M Dener

Michael S Tempesta

Diana M Fort

Wayne D Inman

Joseph L Evans

Thomas J Carlson

Shivanand D Jolad

Thien V Troung

John E Kuo

Guohua Mao

Presented herein are methods for treating diarrhea by administering to a patient in need thereof, an inhibitor of chloride-ion transport in an amount sufficient to treat diarrhea. Treatment of diarrhea includes the treatment of the diarrhea as well as the pain, abdominal discomfort and other symptoms associated with diarrhea. In one embodiment, the inhibitor of chloride-ion transport is crofelemer.

Methods and compositions for treating HIV-associated diarrhea

Novel hypoglycemically active eremophilanolide sesquiterpenes which can be isolated from Psacalium spp., processes for obtaining the novel eremophilanolide sesquiterpenes and methods for their use as hypoglycemic agents, for example, in the treatment of diabetes are described. Further described is the use of epicacalone, cacalone, cacalol or dimaturin as hypoglycemic agents, for example, in the treatment of diabetes. In a preferred embodiment, the hypoglycemically active compounds are obtained from the roots of Psacalium decompositum. As agents for the treatment of diabetes, the hypoglycemically active compounds of the present inventions are useful for treating insulin-dependent (type I) and/or non-insulin-dependent (type II) diabetes.

Furanoeremophilane and eremophilanolide sesquiterpenes for treatment of

Class of phosphocholine derivatives having antifungal activity

The use of extracts from Cryptolepis sp. or quindoline alkaloids such quindoline and cryptolepine contained therein as hypoglycemic agents, as well as methods for obtaining the hypoglycemic agents are described. According to a preferred embodiment, the extracts are derived from Cryptolepis sanguinolenta. As hypoglycemic agents, the extracts or quindoline alkaloids such as quindoline or cryptolepine are useful for treating insulin-dependent (type I) and non-insulin-dependent (type II) diabetes.

Hypoglycemic agent from cryptolepis

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Moss Beach, CA, United States of America

Steven Row King