Pioneer Hi-bred International, Inc.

Syngenta Participations Ag

Other

University of Missouri

University of California

Xencor, Inc.

Steven P Briggs

Gurmukh S Johal

Dilbag Singh Multani

John C Gray

Carl R Simmons

Tong Zhu

Stephen Arthur Goff

Joel Kreps

Darrell Orlyn Ricke

Bret Cooper

Robert J Bensen

Todd Moughamer

Jane Glazebrook

Nicholas Provart

Xun Wang

Jonathan P Duvick

Robert B Meeley

Virginia C Crane

Fumiaki Katagiri

Paul Budworth

John T Tossberg

Donald Adelphi Baldwin

Gongshe Hu

John R Desjarlais

Peter Luginbuhl

Umesh Muchhal

Kiyoshi Tachikawa

Peter Bernard Heifetz

Bipin Dalmia

Fumiyaki Katagiri

Greg Del Val

The invention provides nucleic acids and polypeptides for enhanced expression of nucleic acids and proteins. In one aspect, the sequences serve as transcription and translation enhancers or stabilizers, and can be incorporated in expression constructs at or near the translation control elements. The invention provides methods of producing mRNA (transcripts) and proteins. The invention provides methods of discovering new enhancer elements.

Nucleic acids for inducing expression of transcripts and proteins and methods for making and using them

The present invention provides promoters from plants capable of driving gene expression in plant cells. The promoters vary in strength and in tissue specificity, and can be used to facilitate the development of transgenic plants in which tissue preferred expression, constitutive expression, and the strength of transgene expression is either more or less critical.

Rice promoters for regulation of plant expression

The invention relates to methods of producing plants with increased resistance to pathogen infection by expressing disease resistance genes in the plants and transgenic plants having enhanced pathogen resistance.

Plant disease resistance genes

The invention relates to the genetic modification of plants, particularly to the expression of P-glycoprotein genes in transformed plants. Nucleotide sequences for the Br2 gene encoding a P-glycoprotein of maize and methods for their use are provided. The sequences find use in modifying the growth of plants.

Isolated nucleic acid molecules encoding the Br2 P-glycoprotein of maize and methods of modifying growth in plants transformed therewith

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The present invention relates to the use of a variety of methods for generating functional thioredoxin reductase variants in which at least one physical, chemical or biological property of the variant is altered in a specific and desired manner when compared to the wild-type protein.

Nucleic acids and proteins with thioredoxin reductase activity

The present invention is drawn to methods and compositions for suppressing cell death in plants. Specifically, novel proteins and genes are provided for use in plant transformation. The proteins and genes are useful for activating disease resistance, enhancing plant cell transformation efficiency, engineering herbicide resistance, genetically targeting cell ablations, and other methods involving the regulation of cell death in plants.

Polypeptide compositions for controlling cell death and disease resistance in plants

Compositions and methods for enhancing disease resistance in plants are provided. The method involves transforming a plant with an avirulence gene or alternatively with an avirulence gene and the complementing resistance gene. A pathogen inducible promoter or alternatively a weak constitutive promoter is used to control the desired level of disease control in the plant. Transformed plants, plant cells, tissues, and seed are also provided having enhanced disease resistance.

Methods for enhancing disease resistance in plants

Compositions and methods for enhancing disease resistance in plants are provided. The method involves modulating the activity of sequences in the plant. Particular sequences are provided that can be manipulated to enhance pathogen resistance in modified plants. Transformed plants, plant cells, tissues, and seed are also provided having enhanced disease resistance.

Manipulation of Mlo genes to enhance disease resistance in plants

The invention provides isolated Hm2 nucleic acids, and their encoded proteins. The present invention provides methods and compositions relating to altering Hm2 concentration and/or composition of plants. The invention further provides expression cassettes, host cells, transgenic plants, and antibody compositions. Also, the invention provides methods of identifying plant transformation by survival of transformed plant cells or tissues on a cyclic tetrapeptide toxin. The invention further provides methods of imparting disease resistance to plants susceptible to fungal pathogens, which utilize cyclic tetrapeptide toxins.

Hm2 cDNA and related polypeptide

Histone deacetylases and nucleotide sequences encoding said histone deacetylases are provided. The sequences as well as corresponding antisense constructs are useful for modulating gene activity in plants. Additionally, the sequences are useful for enhancing disease resistance in transformed plants.

Maize histone deacetylases and their use

Compositions and methods for enhancing disease resistance to a pathogen in a plant are provided. Methods of the invention comprise stably transforming a plant with an antisense nucleotide sequence for a gene encoding an enzyme in the C-5 porphyrin metabolic pathway and operably linking said antisense sequence to a pathogen-inducible promoter, such that invasion of a cell by a pathogen elicits a hypersensitive-like response that results in confinement of the pathogen to cells of initial contact. Transformed plants and seeds are provided. Nucleotide sequences encoding a wild-type maize urod gene useful in the present invention and the amino acid sequence for the protein encoded thereby are provided. These compositions are also useful for regulating cell death in specifically targeted tissues. A maize lesion mimic, dominant mutant phenotype, designated Les22, and the molecular basis for its manifestation are also provided.

Methods and compositions for regulating cell death and enhancing disease resistance to plant pathogens

Growing community of inventors

Del Mar, CA, United States of America

Steven P Briggs