Roche Diagnostics Operations, Inc.

Roche Diabetes Care, Inc.

Integrated Vascular Systems, Inc.

Genentech, Inc.

Scimed Life Systems, Inc.

Hill-rom Services, Inc.

Hill-rom, Inc.

Tearscience, Inc.

Boston Scientific Scimed, Inc.

American Life Support Technology

Other

Amira Medical

Dynamic Valves, Inc.

F. Hoffmann-la Roche Ag

Wigwam Mills, Inc.

Steven Nelson Roe

Charles C Raney

Jeffrey N Roe

W Martin Belef

Hans List

Robert J Ferrand

Marc M Thomas

William N Aldrich

Volker Zimmer

Lincoln J Alvord

Richard W O'Connor

William R Fish

Stephen D Smith

William A Gilmartin

William Loh

Wesley E Grass

Richard S Ginn

Ronald J Jabba

Michael T Carley

Uwe Kraemer

Javier Sagastegui

Jonathan Salsado

William Silva

Anthony J Pantages

Christopher D Wiegel

Edward P Perez

Chris Wiegel

Charles W Neder

Donald R Korb

Stephen Michael Grenon

Thomas C Moore

Terry Allen Beaty

William Martin Belef

Niyazi Beyhan

John H Ream

Jeffrey M Jones

Lyle Paul

Arcadi Elbert

Charles Neder

Lionel Vedrine

Hans-Peter Haar

Emad Sarofim

Frank A Chan

Lawrence D Wasicek

Stephen M Salmon

Donald S Mamayek

Mukund R Patel

Stephan-Michael Frey

Patrick Griss

Rainer Jaeggi

James D Koger

Marco De Polo

Otto Fuerst

Chris Fruhauf

Geraint Iwan Davies

Theo Arnitz

Irio Guiseppe Calasso

Sherri Biondi

Jonathan Salzedo

John E Looper

Celia Oakley

Dave Hasker

Wilfried Schmid

Michael Keil

Daniel ManHung Wong

Thomas Weiss

Michael Marquant

Abner D Joseph

Hans-Juergen Kuhr

Irio Giuseppe Calasso

Peter Sachsenweger

Richard Forster

Christian Hoerauf

Ian Michael Munson

Martin Kopp

Max G Chen

Guangqun Chen

Francisco Javier Sagastegui

Matthew L Kaplan

Hansjoerg Braendle

Patrick Klein

Thomas Dwight

Dean T Miller

Dean I Miller

Marco DePolo

Wilifried Schmid

Wilhelm Hildebrandt

Matt Hannant

A Michael Jung

Rafael C Donnay

David S Fisher

Drug delivery systems, devices and methods of use for recording a drug dose completion signal in a data management system are provided. Aspects of the invention include drug delivery systems comprising a syringe stopper rod that comprises a sensor component comprising a wireless transmitter module and an activation component configured to activate the sensor component when the syringe stopper rod has completed a delivery stroke, wherein the wireless transmitter module is configured to transmit a report comprising a drug dose completion signal when the sensor component is activated.

Injection monitoring device

Drug delivery systems and methods of use thereof for recording administration of a drug dose to a subject are provided. Aspects of the invention include a syringe stopper rod comprising a sensor component that is configured to detect a delivery signature, and to transmit a report comprising a drug dose completion signal to a data management component, e.g., a mobile computing device.

Injection monitoring device with delivery signature

Apparatus and methods for medicament delivery. The apparatus may include, and the methods may involve, a delivery device for delivering a target amount of the medicament from a distal end of the device. The device may include a rod for moving a plunger that discharges the medicament from the distal end. The device may avoid or reduce deformation of the plunger during the discharge. The plunger motion may be stopped by detent that interacts with the rod. The apparatus and the methods may provide an operator indication of progress of stages of operation. The device may feature triggers corresponding to stages of medicament displacement from the device, such as pre-delivery stages, including priming.

Versatile syringe platform

A medical device that includes a plurality of members forming a body that can transition from a delivery configuration to a deployed configuration. The plurality of members form a plurality of openings each with a long axis extending substantially longitudinally relative to a longitudinal axis of the medical device in a delivery configuration. A plurality of end portions are associated with a distal portion of the medical device, the end portions extending towards the longitudinal axis in a deployed configuration.

Closure device and methods for making and using them

A method of assembling a lancet housing assembly comprising multiple lancets for use in a portable handheld medical diagnostic device for sampling bodily fluids from a skin site of a patient is disclosed. The method includes forming a plurality of lancet structures in a lancet sheet. The lancet sheet has a removable ledge for releasing the lancet structures. The removable ledge of the lancet sheet is flexed for releasing the lancet structures from the removable ledge.

Methods and structures for assembling lancet housing assemblies for handheld medical diagnostic devices

A method of controlling lancing speed of a lancing structure of a portable handheld medical diagnostic device includes providing an elongated lancet structure having a skin piercing end and a blood transport portion adjacent the skin piercing end. The skin piercing end when displaced makes an incision at a skin site to produce an amount of bodily fluid from the skin site and in which the blood transport portion transports the amount of bodily fluid away from the skin site for use by a measurement system in making a physiological measurement. A spring-driven motor assembly is operatively connected to the lancet structure. The spring-driven motor assembly displaces the lancet structure toward the skin site to make the incision for producing the amount of bodily fluid and retracts the lancet structure to carry the amount of bodily fluid away from the skin cite. A speed control mechanism is engaged with the spring-driven motor assembly as the spring-driven motor assembly retracts the lancet structure thereby decelerating the lancet structure as the lancet structure is retracted away from the skin site.

Handheld medical diagnostic devices with lancing speed control

Systems and methods for providing in-road electric conductivity boxes and on-vehicle descent and pivot contacts for vehicles are provided. In one example embodiment, a system includes, inter alia, a charging component physically coupled to a roadway, a power source electrically coupled to the charging component, and a vehicle that electrically couples with the charging component for receiving power from the power source via the charging component when the vehicle is on the roadway at a location proximate to the charging component. Additional embodiments are also provided.

Systems and methods for providing in-road electric conductivity boxes and on-vehicle descent and pivot contacts for vehicles

A method that includes locating an opening in tissue by advancing a member through the opening in tissue and following locating the opening, deploying a medical device to aid with sealing the opening. The medical device includes a plurality of strut members forming a plurality of generally diamond-shaped openings, the plurality of strut member being configured to form an annular shaped structure with the generally diamond-shaped openings extending generally longitudinally relative to a longitudinal axis of the medical device. The medical device further includes a plurality of tissue engaging portions associated with the plurality of struts, each tissue engaging portion being disposed between adjacently positioned generally diamond-shaped openings.

A closure system and methods of use are provided for use in sealing an opening in a body tissue, such as a vascular puncture site. A method of closing the opening in the body tissue can be performed with the closure system having a closure clip. The method can include positioning the closure clip in a first closure clip position adjacent to the opening in the body tissue such that a plurality of spikes of the closure clip are inserted into the tissue at a location outward from a central axis of the opening. Subsequently, the closure clip can be positioned in a second closure clip position such that the plurality of spikes are pulled inward toward the central axis of the opening so as to pull the tissue between the opening and each of the spikes together and close the opening.

Closure system and methods of use

A medical device that includes a plurality of strut members forming a plurality of generally diamond-shaped openings, the plurality of strut member being configured to form an annular shaped structure with the generally diamond-shaped openings extending generally longitudinally relative to a longitudinal axis of the medical device. A plurality of tissue engaging portions are associated with the plurality of struts, with each tissue engaging portion extending towards the longitudinal axis in a deployed configuration.

A bodily fluid sampling device is operable to lance with a precise depth and express fluid from both fingertip and alternate sites. In one form, the device is operable to adjust the penetration depth of the lancet into the skin. The bodily fluid sampling device includes a lancet adapted to form an incision in skin. A skin contacting member has an orifice through which the lancet extends when lancing the skin. The orifice has a first opening size that is sized to flatten the skin around the lancet during lancing. The orifice has a second opening size that is larger than the first opening size after the incision is formed to express fluid from the incision.

Precision depth control lancing tip

A lancet housing assembly for use in a portable handheld medical diagnostic device for sampling bodily fluids from a skin site of a patient is provided. The lancet housing assembly comprises an outer facing side and an inner facing side. An opening is located at the outer facing side that is arranged and configured to align with a lancet port of the medical diagnostic device. A floor extends between the outer facing side and the inner facing side and having a reagent material. A lancet structure having a skin penetrating end and a blood transport portion adjacent the skin penetrating end is located in housing assembly. The blood transport portion is arranged and configured receive the amount of blood from the skin penetrating end and to carry the amount of blood away from the skin site and to the reagent material.

Handheld medical diagnostic device with lancet and sample transfer

Growing community of inventors

San Mateo, CA, United States of America

Steven Nelson Roe