Case Western Reserve University

Dartmouth College

Steven N Fiering

Nicole F Steinmetz

Amy M Wen

Patrick H Lizotte

Jose R Conejo-Garcia

John B Weaver

William G North

David J Bzik

Barbara A Fox

Jason Baird

Adam M Rauwerdink

Uciane K Scarlett

A method of treating cancer in a subject in need thereof includes administering in situ to the cancer a therapeutically effective amount of a virus or virus-like particle.

Cancer immunotherapy using virus particles

A method of treating cancer in a subject that includes administering in situ to the cancer a therapeutically effective amount of a plant virus or virus-like particle to the subject.

The present invention a method for producing a human immunoglobulin G (IgG) antibody using a prime-boost regime in a Bone Marrow Liver Thymic (BLT) mouse.

Method for producing human monoclonal immunoglobuling antibodies

The present invention provides attenuatedmutants for use as vaccines in the prevention or treatment of cancer.

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A method for diagnosing certain types of cancers provides a nanoparticle agent to be uptaken by cancer cells for diagnosis and treatment of certain cancers. A compound containing nanoparticles is directed toward a tumor site, and then a predetermined time period passes to allow the nanoparticles to be uptaken by the cancer cells. Imaging is then performed on the nanoparticles by an appropriate imaging device to determine the concentration of nanoparticles uptaken by the cancer cells. Finally, image data provided by the imaging device is analyzed to determine the concentration of nanoparticles and thereby determine whether a tumor is present. The nanoparticle agent can further be employed as a treatment of certain cancers. After the uptake of nanoparticles into the cells, a predetermined field applied to the nanoparticles for a sufficient period of time activates the magnetic cores of the nanoparticles to include hyperthermia-mediated destruction of the cancer cells.

Growing community of inventors

Orange, NH, United States of America

Steven N Fiering