Abbott Laboratories Corporation

Steven N Anderson

Joseph P Schaller

Milo Duane Hilty

Jin-Zhou Liu

Melinda Guzman-Harty

Terry Bruce Mazer

Lisa Ann Reaves

Jonathan A Meulbroek

Pradip Mukerji

Yung-Sheng Huang

Shie-Ming Hwang

Jim-Wen Liu

Theresa Siu-Ling Lee

Theresa Siu-Ling Wai Lee

Theresa Sui-Ling Wai Lee

Jill M Lamm

Tammy Marie Bowman

Patricia Joan Ewing

Antibacterial phosphoinositides

It has been discovered that certain phosphoinositides demonstrate antibacterial activity. Particularly, these phosphoinositides have been discovered to prevent the adhesion of,onto the nasopharyngeal cells of mammals, and, in particular, humans. Phosphoinositides useful with the present invention have the following formula:

The present invention is directed to a rice flour extract (RFE) which can be used in the prophylaxis and treatment of bacterial infections, particularly bacterial infections caused by,and to a method of preparing and using such an antibacterial rice flour extract. The anti-,rice flour extract of the present invention can be prepared from commercial food grade rice flours or non-commercial food grade rice flours.

Bioactive rice flour extract useful for treatment of haemophilus influenzae infections

A nutritional formulation containing bactericidal amounts of diacetyltartaric acid esters of mono- and diglycerides is provided. A process of inhibiting bacterial infections including the step of feeding the nutritional composition to a subject is also provided.

Nutritional formulations containing water-miscible lipid derivatives as antibacterial agents

A process of treating infection by a pathogenic microorganism in a subject in need of such treatment comprising the step of administering to the subject an effective antimicrobial amount of diacetyltartaric acid esters of mono- and diglycerides is provided. Pharmaceutical compositions containing diacetyltartaric acid esters of mono- and diglycerides as an active antimicrobial agent are also provided.

Water-Miscible esters of mono- and diglycerides having antimicrobial

A nutritional formulation containing bacterial amounts of diacetyltartaric acid esters of mono- and diglycerides is provided. A process of inhibiting bacterial infections including the step of feeding the nutritional composition to a subject is also provided.

Nutritional formulations containing water-miscible lipid derivatives as

A process of treating infection by a pathogenic microorganism in a subject in need of such treatment including the step of administering to the subject an effective antimicrobial amount of diacetyltartaric acid esters of mono- and diglycerides is provided. Pharmaceutical compositions containing diacetyltartaric acid esters of mono- and diglycerides as an active antimicrobial agent are also provided.

Water-miscible esters of mono- and diglycerides having antimicrobial

The present invention provides water-miscible lipid derivatives effective to inhibit the infectious activity of pathogenic microorganisms. Preferred water-miscible lipid derivatives are diacetyltartaric acid esters of monoglycerides wherein 90 percent or more of the fatty acid content is accounted for by a single fatty acid. The fatty acid component preferably contains from 8 to 24 and, more preferably, from about 10 to about 20 carbon atoms. The fatty acid can be saturated, unsaturated or hydroxylated.

Water-miscible esters of monoglycerides having antimicrobial activity

A process of treating a bacterial infection in a subject in need of such treatment including the step of administering to the subject an effective bactericidal amount of diacetyltartaric acid esters of mono- and diglycerides is provided. Pharmaceutical compositions containing diacetyltartaric acid esters of mono- and diglycerides as an active bactericidal agent are also provided.

Water-miscible esters of mono--and diglycerides having antibacterial

A nutritional formulation containing an amount of diacetyltartaric acid esters of mono- and diglycerides effective to inhibit the infectious activity of pathogenic microorganisms is provided. A process of inhibiting the infectious activity of pathogenic microorganisms including the step of feeding the nutritional composition to a subject is also provided.

Growing community of inventors

Aurora, IL, United States of America

Steven N Anderson