Paracor Medical, Inc.

Asahi Medical Technologies, Inc.

Imperative Care, Inc.

Retrovascular, Inc.

Steven Meyer

Lilip Lau

Wayne Ogata

Xiang Ian Gu

Matthew G Fishler

Craig E Mar

Anuja H Patel

James K Hong

Kyle Bartholomew

Alireza Yavari

Ian Peter Van Sciver

Osamu Katoh

Sieu T Duong

Paul J Lingane

Sieu Dong

A method of priming an interventional device assembly includes providing the interventional device assembly including a first interventional device coupled to a first hub and a second interventional device coupled to a second hub arranged in a concentric stack, the second interventional device being positioned within a lumen of the first interventional device. The method includes coupling the interventional device assembly to a drive system while arranged in the concentric stack, axially advancing the first interventional device and the first hub relative to the second hub to decrease a depth of insertion of the second interventional device within the lumen of the first interventional device while maintaining a distal end of the second interventional device within the lumen of the first interventional device, and flushing the first interventional device with fluid after decreasing the depth of insertion of the second interventional device within the lumen of the first interventional device.

Method of priming concentrically stacked interventional devices

A method of priming an interventional device assembly includes providing the interventional device assembly, the interventional device assembly including a first interventional device and a second interventional device, the second interventional device being positioned within the first interventional device. The method further includes reciprocally moving at least one of the first interventional device and the second interventional device relative to the other of the first interventional device and the second interventional device while flushing a lumen between the first interventional device and the second interventional device with fluid to remove microbubbles from the lumen.

Method of priming an interventional device assembly

Methods and devices that provide enhanced delivery of a composition to a body region of a patient utilizing radiofrequency energy include directing a first electrode and a second electrode coupled to a radiofrequency energy source to a location proximate to the body region. Radiofrequency energy is provided in modulated pulses from the radiofrequency energy source to the body region from at least one of the first electrode and the second electrode to provide a delivery condition configured to enhance delivery of the composition. The composition is delivered proximate to the body region using a composition delivery element. Devices for enhance composition delivery are also disclosed.

Method and device for enhanced composition delivery

A radiofrequency guidewire includes a core wire configured to be coupled to a radiofrequency generator. The core wire includes a proximal end and a distal end with respect to the radiofrequency generator. A tip structure is coupled to the core wire proximate the distal end. The tip structure includes one or more edge surfaces. The one or more edge surfaces provide an area of reduced curvature radius on the tip structure. The area of reduced curvature radius generates a higher electric field than other areas of the tip structure during a delivery of radiofrequency energy on the tip structure. A method of ablating an occlusion utilizing the radiofrequency guidewire is also disclosed.

Radiofrequency guidewire with controlled plasma generation and methods of use thereof

A redirecting delivery catheter includes a first longitudinal member having an inner chamber configured to receive a second longitudinal member, an outer surface surrounding the inner chamber, a first region located at a proximal end, a second region located at a distal end, and a length. An opening in the outer surface extends along a portion of the length of the first longitudinal member between the first region and the second region. A deflecting mechanism is located proximate to the opening and is configured to be capable of transforming from a first position to a second position. The deflecting mechanism is configured to enable the second longitudinal member to access the second region in the second position and to deflect the second longitudinal member towards the opening in the first position. Methods of use of the redirecting delivery catheter are also disclosed.

Redirecting delivery catheter and methods of use thereof

An apparatus comprises a first longitudinal member and a second longitudinal member configured to be located near a tissue region. An energy source is coupled to first longitudinal member and second longitudinal member. A measuring device is configured to measure at least one characteristic of the tissue region. An energy controller is coupled to the energy source and the measuring device. The energy controller includes a processor coupled to a memory and configured to execute programmed instructions stored in the memory, comprising initiating a delivery of energy to the tissue region from the energy source. One or more items of data are received from the measuring device based on the delivery of energy to the tissue region. The delivery of energy to the tissue region is adjusted based on the one or more items of data.

Methods for tissue ablation measurement and control and devices thereof

A method and apparatus for measuring an impedance of a tissue region inside a body of a patient. A first guidewire is advanced into a tissue region of a body of a patient, wherein the first guidewire comprises one or more electrodes electrically coupled to the tissue region. A second guidewire is advanced into the body, wherein the second guidewire comprises one or more electrodes electrically coupled to the tissue region of the body of the patient and spaced from the first guidewire. An error correction electrode is electrically coupled to the body. A voltage is applied across the first and the second guidewires. The impedance of the tissue region between the first and the second guidewires is measured while using an electrical pathway created by the error correction electrode.

Methods for measuring tissue impedance and devices thereof

A cardiac harness for treating or preventing congestive heart failure is configured to be placed about at least a portion of a patient's heart so as to apply a mild compressive force on the heart. In one embodiment, the cardiac harness comprises a plurality of spaced apart conductive panels arranged so that there is no electrical continuity circumferentially around the harness. In an additional embodiment, a cardiac harness is provided that is insulated so as not to conduct electricity circumferentially about the harness.

Cardiac harness

A self-anchoring cardiac harness is configured to fit at least a portion of a patient's heart and includes a tissue engaging element for frictionally engaging an outer surface of a heart. The engaging element produces sufficient friction relative to the outer surface of the heart, so that the harness does not migrate substantially relative to the heart. There is enough force created by the engaging element that there is no need to apply a suture to the heart in order to retain the cardiac harness. Further, the engaging element is adapted to engage the outer surface of the heart without substantially penetrating the outer surface.

Self-anchoring cardiac harness

A cardiac harness for treating a patient's heart includes elastic rows connected by a connector assembly. The connector assembly can have a specific pattern, or can be formed of elongated elastic material connecting all of the apices of adjacent rows. The connectors maintain proper spacing between rows or rings on the harness and provide longitudinal stability.

Growing community of inventors

Oakland, CA, United States of America

Steven Meyer