The Perkin-elmer Corporation

Becton Dickinson and Company Limited

Roche Diagnostic Systems, Inc.

Other

Roche Dianostic Systems, Inc.

Applera Corporation

Roche Diagnostics Gmbh

Perkinelmer Instruments LLC

Steven M Rosen

Joseph L Di Cesare

Allison A Peckham

Alois G Prais

Volker Niermann

Stewart E Marsden

Sharon A Innamorato

The present invention is a collection assembly comprising a container, a cap assembly removably and sealably secured to the container whereby access to the interior of the container can be made with a piercing element without removing the cap assembly from the container. The cap assembly includes a cap body and a membrane like septum supported by the cap body. The septum provides for a pierceable element to have access to the interior of the container. The membrane is a thermoplastic elastomer and is self-sealing upon removal of the piercing element.

Collection assembly

The present invention is a collection assembly comprising a container, a cap assembly removably and sealably secured to the container, whereby access to the interior of the container can be made with a piercing element without removing the cap assembly from the container. The cap assembly includes a cap body and a membrane like septum supported by the cap body. The septum provides for a pierceable element to have access to the interior of the container. The membrane is a thermoplastic elastomer and is self-sealing upon removal of the piercing element.

A blood collection assembly designed for one-time use includes a microcollection tube and an adapter for the tube which is sized to fit into the tube slot of an automated analytical instrument. The adapter includes structure which forms a tight and permanent interference fit with the microtube so that the tube, once inserted into the adapter, cannot be removed by hand, and the assembly, after sampling and analysis, must be discarded in one piece.

Microcollection tube assembly

Apparatus and method for detection of low levels of about 1 ppb of analyte in samples using an enclosed permeable membrane enrichment device and agglutination reaction slide test apparatus.

Detection of low level analytes in samples using agglutination reaction

The presence or absence of an organism in a sample is detected by isolating the organism from the sample by a suitable affinity matrix, releasing the organism from the affinity matrix, rupturing the cells of the organism to release total nucleic acid and hydrolyzing or digesting the total nucleic acid to form mononucleotides or individual free nucleic acid basic and inorganic phosphate to form an analyte solution, and assaying the analyte solution for the at least one presence of free nucleic acid base or inorganic phosphate to thereby determine whether the organism was present in the sample.

Method of detecting organisms in a sample

Apparatus and method for detection of low levels of about 1 ppb of hydrophobic analyte in environmental samples using an enclosed permeable membrane enrichment device and agglutination reaction slide test apparatus.

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Mountain Lakes, NJ, United States of America

Steven M Rosen