Eli Lilly and Company

Steven Lee Kuklish

Matthew Joseph Fisher

Jeremy Schulenburg York

Ryan Thomas Backer

Michael J Martinelli

Jeffrey Thomas Mullaney

Vincent Mancuso

Christopher William Doecke

Matthew Allen Schiffler

Chaoyu Xie

Katherine Marie Partridge

Paul Leslie Ornstein

Alan M Warshawsky

Karin Briner

Peter Rudolph Manninen

Kumiko Takeuchi

Edward C R Smith

Sean Patrick Hollinshead

Maria-Jesus Blanco-Pillado

Zhipei Wu

Albert Khilevich

Ana Isabel Mateo Herranz

Steven James Quimby

Tatiana Natali Vetman

Cristina Garcia-Paredes

Kenneth James Henry, Jr

Ivan Collado Caño

Oscar De Frutos Garcia

Caño Ivan Collado

Oscar De Frutos-Garcia

Kenneth James Henry

The invention provides BTK Inhibitor compounds of the formula 

BTK inhibitor compounds

The present invention provides compounds of Formula 1, or a pharmaceutically acceptable salts, thereof, where R, X, A, E, and G are as described herein, methods of preparing the compounds, and use of the compounds to treat pain and/or inflammation. 

Carboxylic acid compounds useful for inhibiting microsomal prostaglandin E2 synthase-1

The present invention provides compounds of Formula (1), or a pharmaceutically acceptable salt thereof, formula (1), where R, R1, and G are as described herein; methods of preparing the compounds; and use of the compounds to treat pain and/or inflammation associated with arthritis or osteoarthritis. 

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The present invention provides a compound of the Formula (I): wherein X, R, R, R, R, R, R, R, R, R, and Rare as defined herein, or a pharmaceutically acceptable salt thereof. 

Phenoxyethyl cyclic amine derivatives and their activity as EP4 receptor modulators

The present invention provides a compound of the Formula II:  

Dimethyl-benzoic acid compounds

The present invention provides compounds of the formula below or pharmaceutical salts thereof, wherein R1, R2 and R3 are as described herein; methods of treating osteoarthritis using the compounds; and a process for preparing the compounds.

Imidazole-2-benzamide compounds useful for the treatment of osteoarthritis

This application relates to a substituted carboxamide compound of formula I, or a pharmaceutically acceptable salt thereof, as defined herein, a pharmaceutical composition thereof, and its use in treating pain.

Substituted carboxamides

The present invention relates to melanocortin receptor agonist of the formula (I): which is useful in the treatment for obesity, diabetes, and male and/or female sexual dysfunction 

Melanocortin receptor agonists

The present invention relates to melanocortin receptor agonist of the formula I useful in the treatment of obesity, diabetes, and male and/or female sexual dysfunction 

The present invention relates to melanocortin receptor agonists of formula I, which is useful in the treatment of obesity, diabetes and male and/or female sexual dysfunction 

Substituted piperidines/piperazines as melanocortin receptor agonists

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Fishers, IN, United States of America

Steven Lee Kuklish