Boehringer Ingelheim International Gmbh

Boehringer Ingelheim Pharma Gmbh & Co Kg

Steven John Taylor

Qiang Zhang

Asitha Abeywardane

Lana Louise Smith Keenan

Alexander Heim-Riether

Ming-Hong Hao

Hidenori Takahashi

Zhaoming Xiong

Donghong Amy Gao

Anil Kumar Padyana

Chuk Chui Man

Neil Alexander Farrow

Michael Robert Turner

Renee M Zindell

Dieter Wiedenmayer

Hossein Razavi

Tina Marie Morwick

Robert Sibley

Thomas Martin Kirrane, Jr

Roger John Snow

Erick Richard Roush Young

Ronald John Sorcek

Yunlong Zhang

Michael Jason Burke

Ho Yin Lo

Stephane De Lombaert

Daniel Richard Marshall

Michel Jose Emmanuel

Peter Allen Nemoto

Brian Nicholas Cook

Bernd Wellenzohn

Steven Richard Brunette

Ingo Andreas Mugge

Jin Mi Kim

Xin Guo

Shuang Liang

Sabine K Schlyer

Kevin Chungeng Qian

Yang Yu

Bennett Farmer

Michael Jason Bruke

Donghong A Gao

The present invention relates to compounds of formula (I): or a pharmaceutically acceptable salt thereof, wherein A, A, Land B are as defined herein. The compounds of formula (I) are useful as inhibitors of leukotriene Ahydrolase (LTAH) and treating LTAH related disorders. The present invention also relates to pharmaceutical compositions comprising the compounds of formula (I), methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.

Inhibitors of leukotriene production

Disclosed are small molecule inhibitors which are useful in treating various diseases and conditions involving chymase.

Benzimidazolone chymase inhibitors

The present invention relates to compounds of formula I or a pharmaceutically acceptable salt thereof, wherein A, A, A, L, Land D are as defined herein. The compounds of formula (I) are useful as inhibitors of leukotriene Ahydrolase (LTA4H) and treating LTA4H related disorder. The present invention also relates to pharmaceutical compositions comprising the Compounds of formula (I), methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds. 

Arylpyrazole ethers as inhibitors of leukotriene A4 hydrolase

Disclosed are small molecule inhibitors which are useful in treating various diseases and conditions involving chymase.  Also disclosed are pharmaceutical compositions, methods of using and making the same.

Chymase inhibitors

Disclosed are compounds and compositions of the formula I as described herein which are inhibitors of MMP-13. Also disclosed are methods of using and making compounds of the formula I. 

Heteroaryl substituted indole compounds useful as MMP-13 inhibitors

Disclosed are compounds and compositions of the formula (I) as described herein which are inhibitors of MMP-13. Also disclosed are methods of using and making compounds of the formula (I). 

Heteroaryl diamide compounds useful as MMP-13 inhibitors

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Southbury, CT, United States of America

Steven John Taylor