Cilag International Gmbh

Lifescan Scotland Limited

Other

Steven John Setford

Graeme J Webster

David Elder

Ryan T Walsh

Allan James Faulkner

Marco Fabio Cardosi

Christopher Philip Leach

James T Moffat

Gavin Macfie

Lawrence Ritchie

Selwayan Saini

John Scott

Scott J Sloss

Anthony Peter Turner

Stephen A White

Susan Alcock

Jon Dicks

Ibtisam Tothill

Phillip Warner

Sarah Stephens

Jennifer Hall

Ryan Walsh

The invention provides electrochemical-based modules useful for the determination of an analyte in a bodily fluid sample. The modules of the invention provide opposed electrodes, but the contact areas for making electrical contact between the electrodes and the analyte measurement device are coplanar.

Electrochemical sensors and a method for their manufacture

A test strip port connector of a test meter receives an analytical test strip comprising a sample chamber for receiving a fluid sample. The fluid sample is prevented from contaminating an interior region of the test strip port connector by a sealing mechanism having a seal configured to be moved into a sealing position across the test strip.

Test strip connector contact protection

An analytical test strip has mutually-insulated first and second electrodes arranged to define a sample-receiving chamber. Electrically-insulating layers are disposed over respective electrodes. First and second electrical contact pads are electrically connected to the first electrode, and a third pad to the second electrode. A first side of the test strip has a first electrically-insulating layer and the third pad, and a second side has the second electrically-insulating layer and the first and second pads. The third pad extends longitudinally from the sample-receiving chamber farther than does the first electrically-insulating layer. Methods for determining an analyte in a bodily-fluid sample and analytical test systems for use in the determination of an analyte in a bodily-fluid sample are also described.

Analytical test strip

A test strip having conductive surfaces separated by a spacer layer, wherein the spacer layer is comprised of sections forming a plurality of sample chambers that enable the test strip to be inserted into a test meter in a number of possible orientations. The test strip also includes electrical contact pads on opposing sides thereof such that the test meter may separately engage the contact pads depending on the insertion orientation.

Multi-orientation test strip

An analytical test strip can include a patterned definition layer defining two fluidically-separated sample cells having respective ports, a common electrode arranged over the definition layer and in electrical communication with each of the cells, and respective cell electrodes. Surface portions of each electrode can be exposed. A method for testing a fluid sample using such a strip includes receiving a first fluid sample in the first sample cell and detecting a first electrical property thereof. It is then determined whether a second fluid sample should be added to the other sample cell. An analyte measurement system can include such a strip and test meter to receive the strip. The test meter can detect respective electrical properties of fluid samples in the cells.

Dual-chamber analytical test strip

A test meter for use with a dual-chamber, multi-analyte test strip includes a test strip receiving module and a signal processing module. The test strip receiving module has a first electrical connector configured for contacting a first analyte contact pad of a first working electrode of the test strip; a second electrical connector configured for contacting a second analyte contact pad of a second working electrode of the test strip, a third electrical connector configured for contacting a first counter/reference contact pad of a first counter/reference electrode layer of the test strip, and a fourth electrical connector configured for contacting a second counter/reference contact pad of a second counter/reference electrode layer of the test strip. The signal processing module is configured to receive a first signal via the first electrical connector and the third electrical connector and employ the first signal for the determination of a first analyte (such as glucose) in a bodily fluid sample (for example, whole blood sample) applied to the dual-chamber, multi-analyte test strip. Moreover, the signal processing module is also configured to receive a second signal via the second electrical connector and fourth electrical connector and employ the second signal for the determination of a second analyte (e.g., a ketone analyte) in the bodily fluid sample applied to the dual-chamber, multi-analyte test strip. Furthermore, the third and fourth electrical contacts provide contact in an opposing manner.

Test meter for use with a dual chamber, multi-analyte test strip with opposing electrodes

A dual chamber, multi-analyte test strip has a first insulating layer, a first electrically conductive layer, with a first working electrode, disposed on the first insulating layer and a first patterned spacer layer positioned above the first electrically conductive layer. The first patterned spacer layer has a first sample-receiving chamber, with first and second end openings, defined therein that overlies the first working electrode. The test strip also includes a first counter/reference electrode layer that is exposed to the first sample receiving chamber and is in an opposing relationship to the first working electrode. The test strip further includes a counter/reference insulating layer disposed over the first counter/reference electrode layer and a second counter/reference electrode layer disposed on the counter/reference substrate. Also included in the test strip is a second patterned spacer layer that is positioned above the second counter/reference electrode layer. The second patterned spacer layer has a second sample-receiving chamber, with first and second end openings, defined therein. The test strip additionally has a second electrically conductive layer, with a second working electrode, disposed above the second patterned spacer layer, a second insulating layer disposed above the second electrically conductive layer, a first analyte reagent layer disposed on the first working electrode within the first sample-receiving chamber; and a second analyte reagent layer disposed on the second working electrode within the second sample-receiving chamber. The second counter/reference electrode layer is exposed to the second sample receiving chamber and is in an opposing relationship to the second working electrode.

Dual chamber, multi-analyte test strip with opposing electrodes

A backing sheet (101) is provided with a pattern of pathways (131,132,133) of (e.g.) silica or cellulose by a printing process (e.g., screen printing). There may be multiple pathways leading from an eluant application region (117) to a detection zone (116) and thence to a waste reservoir (118). Different pathways may have different fluid traversal times because they differ in length and/or material (e.g., nitrocellulose for slow traversal and fibrous cellulose for rapid traversal by an aqueous liquid). Thus analyte and reagents deposited at depots (112,113) on different pathways are sequentially delivered to the detection zone. Reagents may be applied by printing. The detection zone may have an electrode assembly (105), also applied by printing, for detecting the effects of analyte.

Printed fluid transport devices

Growing community of inventors

Fortrose, United Kingdom

Steven John Setford