Baxter International Inc.

Baxter Healthcare Sa

Steven H Giovanetto

Sidney T Smith

Larry A Rosenbaum

Gregg Nebgen

Bradley H Buchanan

Sue Rosenbaum, Legal Representative

Suchuan C Fan

Y Samuel Ding

David V Bacehowski

William S Hurst

Adel M Sadik

William S Hoerle

Varsha Kalyankar

Melissa J Skelnik

The present invention provides a receptacle () for a therapeutic fluid susceptible to deterioration on exposure to a gas such as oxygen or carbon dioxide. The receptacle () has walls of sheet material each including at least one layer forming a barrier essentially impermeable to such gas, and a seal sealing the walls together in a region thereof. A transfer tube () is sealed in the seal having a proximal end in the receptacle (), a distal end accessible from outside the receptacle (), a flow passage () extending between said proximal and distal ends, and a closure () blocking flow through the flow passage () adapted to be pierced by a tubular needle for transfer of therapeutic through the needle. The transfer tube () and closure () are essentially impermeable to said gas.

Multiple layer polymeric structure

The present invention provides a receptacle for a therapeutic fluid susceptible to deterioration on exposure to a gas such as oxygen or carbon dioxide. The receptacle has walls of sheet material each including at least one layer forming a barrier essentially impermeable to such gas, and a seal sealing the walls together in a region thereof. A transfer tube is sealed in the seal having a proximal end in the receptacle, a distal end accessible from outside the receptacle, a flow passage extending between said proximal and distal ends, and a closure blocking flow through the flow passage adapted to be pierced by a tubular needle for transfer of therapeutic through the needle. The transfer tube and closure are essentially impermeable to said gas.

High gas barrier receptacle and closure assembly

A multilayered film ( ) suitable for medical uses is coextruded in a machine direction and comprises a first layer ( ) defining a pair of peripheral edges ( ) extending in a direction parallel to the machine direction. The film has a second layer ( ) adhered to the first layer ( ). The second layer ( ) is positioned within the peripheral edges ( ) defining a stripe ( ).

Coextruded multilayer film materials and containers made therefrom

The present invention provides a multiple layer structure ( ) for fabricating medical products. The layer structure ( ) has a core layer ( ) of an ethylene vinyl alcohol copolymer having an ethylene content of about 25-45 mole percent, a solution contact layer of a polyolefin positioned on a first side of the core layer, an outer layer ( ) positioned on a second side of the core layer opposite the solution contact layer ( ), the outer layer ( ) being selected from the group consisting of polyamides, polyesters and polyolefins; two tie layers ( )&mdash;one of each adhered to the first and second sides of the core layer ( ) and positioned between the solution contact layer ( ) and the core layer ( ) and between the outer layer ( ) and the core layer ( ), and wherein the structure ( ) is produced in a cast coextrusion process.

Multilayered polymer structure for medical products

The present invention provides a multiple layer structure for fabricating medical products. The layer structure has a core layer of an ethylene vinyl alcohol copolymer having an ethylene content of about 25-45 mole percent, a solution contact layer of a polyolefin positioned on a first side of the core layer, an outer layer positioned on a second side of the core layer opposite the solution contact layer, the outer layer being selected from the group consisting of polyamides, polyesters and polyolefins; two tie layers--one of each adhered to the first and second sides of the core layer and positioned between the solution contact layer and the core layer and between the outer layer and the core layer, and wherein the structure is produced in a cast coextrusion process.

A container (10) suitable for medical uses comprising a first planar member (18), a second planar member (22), a first seam (24) and a second seam (26). The first planar member (18) is of a multi-layered polymeric material and further comprises a first substrate (38) and a first layer (46). The first layer (46) is disposed on a portion of the first substrate (38) to separately define a first overlap area (58) and an adjacent first peripheral flange (62). The second planar member (22) is of a multi-layered polymeric material. The first seam (24) attaches a portion of the first overlap area (58) to the second planar member (22). The second seam (26) is spaced from the first seam (24) and attaches a portion of the first peripheral flange (62) to the second planar member (22).

Perimeter seals for multi-layer materials and method

A container is disclosed comprising a first sidewall having a first layer and a second layer. The second layer overlaps a portion of the first layer to define an overlap area. A sealing flange extends from the first layer outward of the overlap area. A second sidewall is connected to the first sidewall along the sealing flange to define an inner chamber therebetween. The second sidewall and the sealing flange define a first layered structure having a first number of layers along the sealing flange. The overlap area and the second sidewall define a second layered structure having a second number of layers. The second number of layers is greater than the first number of layers. The container is sealed by positioning peripheral edges of the first and second sidewalls into registration so that the overlap area is substantially centrally disposed over the second sidewall and applying sealing energy to the first number of layers to define a peripheral seam.

Encapsulated seam for multilayer materials

A multiple layer structure comprising a skin layer, a barrier layer, a radio frequency susceptible layer having a first polyolefin in an amount within a range of 30-60% by weight, a second polyolefin in an amount within the range of 25-50% by weight, a radio frequency susceptible polymer in an amount within the range of 3-40% by weight, a styrene and hydrocarbon block copolymer in an amount within the range of 5-40% by weight of the sealant layer.

Growing community of inventors

Vernon Hills, IL, United States of America

Steven H Giovanetto