St. Jude Medical, Cardiology Division, Inc.

Steven Frederick Anderl

Peter Nicholas Braido

Mina Safwat Fahim

Neelakantan Saikrishnan

Paul Edward Ashworth

Loell Boyce Moon

Yousef F Alkhatib

Julia Ann Schraut

Thomas M Benson

Ralph Joseph Thomas

Jason White

Jacob John Daly

Kent J Smith

Aditee Kurane

Gary W Geiger

Morgan Low

Jason A White

A prosthetic heart valve may include a collapsible and expandable stent having a proximal end, a distal end, an annulus section adjacent the proximal end, and a plurality of cells connected to one another in annular rows around the stent, a cuff attached to the stent, and a sealing member attached to the cuff and extending from a proximal end of the cuff to a free edge. The sealing member may be movable between an extended condition in which the free edge is located proximally of the proximal end of the stent, and an inverted condition in which the free edge is located distally of the proximal end of the stent and a first surface of the sealing member confronts an outward-facing surface of the cuff. Various mechanisms for moving the sealing member are also described.

Paravalvular sealing via extended cuff mechanisms

A prosthetic valve assembly for implantation in a patient's circulatory system includes a stent, a valve member coupled to the stent and defining a preferred landing zone relative to anatomical structures in the patient's circulatory system, and at least one marker positioned in a predetermined relationship relative to the landing zone of the valve member, the marker being visually distinguishable from the stent using an imaging technique. By observing the marker, the prosthetic valve assembly may be implanted in the patient so that certain ones of the anatomical structures lie within the landing zone.

Method of placing a prosthetic valve assembly in a patient's circulatory system

Prosthetic heart devices may be implanted into the heart with a sensor coupled to the device, the sensor being configured to measure physiological data, such as blood pressure, in the heart. Devices that may employ such sensors include prosthetic heart valves and occlusion devices, although sensor systems may be deployed in the heart separate from other implantable devices. The sensors may include a body with different configurations for attaching to the implantable device, such as apertures for sutures or fingers for connecting to structures of the implantable device. The sensors may provide data that allow a determination of aortic regurgitation or other information indicative of function of the implantable device and patient health during and after implantation of the device.

Sensors for prosthetic heart devices

A prosthetic device for implanting in a patient's heart includes (i) a therapeutic device capable of restoring function to a native heart valve; and (ii) at least one sensor including a body, an inductor coil disposed within the body, and a capacitor in communication with the inductor coil, the at least one sensor being coupled to the therapeutic device, and being configured to monitor proper function of the therapeutic device within the patient's heart.

Prosthetic heart devices having diagnostic capabilities

A prosthetic heart valve includes a stent having a collapsed condition and an expanded condition. The stent has a proximal end, a distal end and a plurality of cells, each cell being formed by a plurality of struts. A valve assembly is secured to the stent and includes a cuff and a plurality of leaflets. The plurality of leaflets are attached to the cuff adjacent an underwire that extends about the perimeter of the cuff.

Valve cuff support

A prosthetic heart valvemay include a collapsible and expandable stenthaving a proximal end, a distal end, an annulus section adjacent the proximal end, and a plurality of cells connected to one another in annular rows around the stent, a cuffattached to the stent, and a sealing memberattached to the cuff and extending from a proximal endof the cuff to a free edge. The sealing membermay be movable between an extended condition in which the free edgeis located proximally of the proximal endof the stent, and an inverted condition in which the free edge is located distally of the proximal end of the stent and a first surfaceof the sealing member confronts an outward-facing surface of the cuff. Various mechanisms for moving the sealing memberare also described.

Radiopaque transcatheter valve and anatomical markers

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Forest Lake, MN, United States of America

Steven Frederick Anderl