E. R. Squibb Sons, Inc.

Eli Lilly and Company

Bristol-myers Squibb Compnay

Other

Serenex, Inc.

Steven E Hall

Michael Robert Wiley

Jason Scott Sawyer

Gerald Floyd Smith

Douglas Wade Beight

James Howard Wikel

Robert T Shuman

John Joseph Masters

David Kent Herron

Ying Kwong Yee

Valentine Joseph Klimkowski

David Mendel

Jennifer Marie Tinsley

Anne Louise Tebbe

Trelia Joyce Craft

Leonard Crayton Weir

Jeffry Bernard Franciskovich

Guy Milot

Jeffrey Alan Kyle

Theodore Goodson, Jr

Martin F Haslanger

Sajan Joseph

Philip Michael Sher

Philip D Stein

Raj N Misra

Jagabandhu Das

Wen-Ching Han

Marta Maria Pi&ntilde;eiro-N&uacute;&ntilde;ez

David M Floyd

Ravi K Varma

Joel C Barrish

Spencer David Kimball

Masami Nakane

Wan Fang Lau

Carl Penman Denny

Marta Maria Pi&ntilde;eiro-Nu&ntilde;ez

Theodore Goodson, Junior

Peter W Sprague

Joyce Reid

Roy Wendell Ware

Martin L Ogletree

Melanie J Loots

Lindsay A Hinkley

Marta Maria Pineiro-Nunez

Matthew G Jenks

Guy Milet

Theodore Goodson Jr

Jeffrey Bernard Franciskovich

Klass P Hardeman

Martin F YHaslanger

Marta Maria Pinelro-Núnez

Alkyl-linked nucleotide non-homogeneous solid supports and nucleotide affinity media comprising an alkyl-linked nucleotide are provided. The linker is generally a hydrophobic linker that can be a 3, 4, 5, 6, 7, 8, 9, 10, or a longer carbon chain. Also included in the invention are methods for synthesis of an alkyl-linked nucleotide, nucleotide affinity media and methods of use thereof for affinity chromatography and screening methods.

Alkyl-linked nucleotide compositions

This application relates to a compound of formula I (or a pharmaceutically acceptable salt thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa, as well as a process for its preparation and intermediates therefor.

Aromatic amides

Antithrombotic amides

This application relates to heteroaromatic amides (or a pharmaceutically acceptable salt thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa, as well as a process for its preparation and intermediates therefor.

Heteroroaromatic amides as inhibitor of factor Xa

This application relates to a compound of formula I (or a prodrug thereof or a pharmaceutically acceptable salt of the compound or prodrug thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa, as well as a process for its preparation and intermediates therefor.

Antithrombotic agents

This application relates to a compound of formula (I) (or a pharmaceutically acceptable salt thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa, as well as a process for its preparation and intermidates thereof.

Growing community of inventors

Ewing Township, NJ, United States of America

Steven E Hall