Millipore Corporation

Steven D Sheridan

Joseph P Lane

Richard Burnham

Christopher A Scott

Louis L Bonhomme

Stéphane Jean Marie Olivier

Kenneth G Desilets

Douglas A Boucher

Luc Lirot

Richard J Shafner

A plate liner detachably engageable onto a microarray plate (or underdrain plate component thereof), suited for preventing or confining pendant drop formation. It is provided either as a stand-alone item, or&#x2014;preferably&#x2014;in kit form, within a sanitary package, together with other pre-matched microarray filtration components.

Detachable engageable microarray plate liner

The present invention provides an underdrain having an improved spout. The underdrain has particular utility in the construction of both single-well and microarray filtration devices. In a principal embodiment, the underdrain is characterized by its incorporation of a straight-walled, roughly-textured spout, the spout being provided with microhole(s) at a terminal end thereof for the discharge of fluid conducted through the underdrain. An array comprising several of such underdrains can be mated with a corresponding array of wells, with separation material (e.g., membrane material) provided therebetween. The resultant microarray filtration device can be used for conducting several fluid assays contemporaneously with, for example, good 'pendant drop' control and low 'cross-talk'.

Underdrain useful in the construction of a filtration device

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Wakefield, MA, United States of America

Steven D Sheridan