Bayer Healthcare LLC

University of Delaware

Ascensia Diabetes Care Holdings Ag

Steven D Brown

Mihailo V Rebec

James E Smous

Hu-Wei Tan

Kristen L Mello

A system for determining the concentration of an analyte in at least one body fluid in body tissue comprises an infrared light source, a body tissue interface, a detector, and a central processing unit. The body tissue interface is adapted to contact body tissue and to deliver light from the infrared light source to the contacted body tissue. The detector is adapted to receive spectral information corresponding to infrared light transmitted through the portion of body tissue being analyzed and to convert the received spectral information into an electrical signal indicative of the received spectral information. The central processing unit is adapted to compare the electrical signal to an algorithm built upon correlation with the analyte in body fluid, the algorithm adapted to convert the received spectral information into the concentration of the analyte in at least one body fluid.

Method for building an algorithm for converting spectral information

System for determining the concentration of an analyte

A system for determining the concentration of an analyte in at least one body fluid in body tissue, the system comprising an infrared light source, a body tissue interface, a detector, and a central processing unit. The body tissue interface is adapted to contact body tissue and to deliver light from the infrared light source to the contacted body tissue. The detector is adapted to receive spectral information corresponding to infrared light transmitted through the portion of body tissue being analyzed and to convert the received spectral information into an electrical signal indicative of the received spectral information. The central processing unit is adapted to compare the electrical signal to an algorithm built upon correlation with the analyte in body fluid, the algorithm adapted to convert the received spectral information into the concentration of the analyte in at least one body fluid.

Non-invasive system for the determination of analytes in body fluids

A data processing and analysis system, and a method of using the same, for discovering implicit relationships in data. The method is executed in a computer system capable of receiving input data comprised of expert knowledge, empirical data, and user-defined constraints for any application domain. The system and method provide any pre-processing the input data may require, and perform feature selection and extraction on the input data. Further, the system and method generate a graphical representation of the implicit relationships in the input data, indicating relationships between both class variables and feature variables. Also generated is a classifier that provides a semantic and statistical justification of its classification results which further provides: statistical relevancy of the data set, including an indication of the undersampled regions of the data space; a data analysis specific to a desired level of confidence; and a sound decision theoretical foundation for classification thresholding. The system and method generate a classifier capable of classifying a sample with respect to any variable, handle missing data values, and provide a complete data analysis.

System for discovering implicit relationships in data and a method of using the same

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Newark, DE, United States of America

Steven D Brown