Hill's Pet Nutrition, Inc.

Colgate Palmolive Company

Hlll's Pet Nutrition, Inc.

Steven Curtis Zicker

Karen Joy Wedekind

Ryan Michael Yamka

Kim Gene Friesen

Dennis Edward Jewell

Nolan Zebulon Frantz

Jeffrey Brockman

Dale Allen Fritsch

Chadwick Everett Dodd

Kathy L Gross

Christina Khoo

Inke Paetau-Robinson

Xiangming Gao

Claudia A Kirk

Philip William Toll

Karen Joy Wedekind Lake

Kathy Lynn Gross

Jeffrey A Brockman

Larry H Hayward

Karen J Wedekind

The invention provides (1) methods for modulating gene expression in senescent mammals by administering antioxidant-comprising compositions to the mammals and (2) antioxidant-comprising compositions that modulate gene expression and/or reduce the oxidative stress of such mammals.

Use of antioxidants for gene modulation

A method for influencing behavior in young, adult or aged pet animals which comprises systemically administering a behavior influencing quantity of an omega-3 fatty acid or mixture of omega-3 fatty acids.

Methods of using omega-3 fatty acids

Compositions and methods useful to enhance neurologic development of a growing animal are disclosed.

Compositions and methods for enhancing neurological development

Compositions and methods useful to enhance the development of the immune system of a growing animal are disclosed.

Compositions and methods for enhancing immune system of felines

The invention encompasses methods for inhibiting histamine release pathways in a companion animal, for example, felines and in treating or preventing idiopathic cystitis or interstitial cystitis. The compositions and methods of the invention include an amount of lipoic acid that is effective in inhibiting histamine release pathways in a companion animal, for example, felines and in treating or preventing idiopathic cystitis or interstitial cystitis.

Antioxidant-containing food composition for use in inhibiting histamine pathways in companion animals

The invention encompasses pet food compositions and methods for the treatment and/or prevention of diseases or disorders in companion animals, for example, for the treatment or obesity, including administering a pet food composition including pyruvic acid or a salt thereof to a companion animal, or lipoic acid or salt thereof and pyruvic acid or a salt thereof to a companion animal. The invention encompasses pet food compositions and methods for managing weight including administering a pet food composition including pyruvic acid or a salt thereof, or lipoic acid or a salt thereof and pyruvic acid or a salt thereof to a companion animal to a companion animal.

Companion animal compositions including pyruvic acid and salts thereof and methods of use thereof

Compositions and methods for increasing lean muscle mass and/or reducing fat gain in growing animals by feeding the animals a composition having a total lysine to metabolizable energy ratio of from about 2.5 to about 6 g/Mcal and comprising (a) arginine in a total arginine to total lysine ratio of from about 1.1 to about 1.6; (b) isoleucine in a total isoleucine to total lysine ratio of from about 0.8 to about 1.3; (c) leucine in a total leucine to total lysine ratio of from about 1.8 to about 3.0; (d) valine in a total valine to total lysine ratio of from about 0.8 to about 1.4; and (e) methionine and cystine in a total methionine plus cystine to total lysine ratio of from about 0.8 to about 1.7.

Compositions and methods for increasing lean muscle mass and/or reducing fat gain

The invention encompasses compositions and methods for treating or preventing kidney disease in a companion animal, wherein the compositions and methods include feeding the companion animal an edible composition including at least one pyruvate or salt thereof.

Compositions including pyruvate for companion animals and methods of use thereof

The invention provides compositions for preventing or treating kidney disease and improving kidney function comprising at least two ingredients selected from the group consisting of antioxidants and mitochondrial cofactors in amounts sufficient for preventing or treating kidney disease or for improving kidney function and methods for preventing and treating kidney disease or improving kidney function comprising administering such compositions to an animal susceptible to or suffering from kidney disease or impaired kidney function. In a preferred embodiment, the composition is admixed with one or more food ingredients to produce a food composition useful for preventing or treating kidney disease and improving kidney function, particularly in senior animals.

Compositions for the treatment of kidney disease

Method of using omega-3 fatty acids

A method for increasing the longevity of an old animal comprising administering to the animal a composition comprising one or more antioxidants in a total antioxidant amount sufficient to increase the longevity of the animal.

Method for prolonging the life of animals

The invention encompasses compositions and methods for treating or preventing disorders in companion animals, wherein the compositions and methods include feeding the companion animal a composition including lipoic acid or a salt thereof.

Companion animal compositions including lipoic acid and methods of use thereof

A food composition comprises an antioxidant component comprising at least one of alpha-lipoic acid and L-carnitine, said composition meeting ordinary nutritional requirements for an adult canine or feline.

Antioxidant-containing food composition

The invention encompasses compositions for enhancing the ability of a companion animal to resist and/or overcome viral infections. The compositions of the invention include an amount of lipoic acid that is effective in enhancing the antiviral immunity of a companion animal.

Antioxidant-containing food composition for use in enhancing antiviral immunity in companion animals

A method for inhibiting a decline in learning and/or memory in an animal comprising maintaining the animal on an antioxidant-fortified diet for a period of at least about 3 years. The diet comprises at least one antioxidant in a total antioxidant amount effective to achieve such inhibition. Suitable antioxidants include vitamin E, vitamin C, &#x3b1;-lipoic acid and antioxidant-containing plant meals. The methods are particularly useful for young adult canines such as dogs.

Growing community of inventors

Lawrence, KS, United States of America

Steven Curtis Zicker