Pfizer Corporation

Pharmacia & Upjohn Company

Steven Charles Reitz

David W Piotrowski

Donn G Wishka

Eric Jon Jacobsen

Vincent E Groppi, Jr

Daniel Patrick Walker

Brad A Acker

Jason K Myers

The invention provides compounds of Formula I: where in W is These compounds may be in the form of pharmaceutical salts or compositions, racemic mixtures, or pure enantiomers thereof. The compounds of Formula I are useful to treat diseases or conditions in which &#x3b1;7 is known to be involved.

Quinuclidines-substituted-multi-cyclic-heteroaryls for the treatment of disease

The invention provides compounds of Formula I:wherein Azabicyclo isW is a six-membered heterocyclic ring system having 1&#x2013;2 nitrogen atoms or a 10-membered bicyclic-six-six-fused-ring system having up to two nitrogen atoms within either or both rings, provided that no nitrogen is at a bridge of the bicyclic-six-six-fused-ring system, and further having 1&#x2013;2 substitutents independently selected from R. These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharmaceuticals to treat diseases or conditions in which &#x3b1;7 is known to be involved.

Azabicyclic compounds for the treatment of disease

The invention provides compounds of Formula I:wherein Azabicyclo isThese compounds may be in the form of pharmaceutical salts or compositions, racemic mixtures, or pure enantiomers thereof. The compounds of Formula I are useful in pharmaceuticals in which &#x3b1;7 is known to be involved.

Azabicyclic-substituted fused-heteroaryl compounds for the treatment of disease

Growing community of inventors

Toledo, OH, United States of America

Steven Charles Reitz