Varian Medical Systems, Inc.

Holaira, Inc.

Calypso Medical Technologies, Inc.

Nuvaira, Inc.

The University of British Columbia

British Columbia Cancer Agency Branch

Innovative Pulmonary Solutions, Inc.

Steven Charles Dimmer

Martin L Mayse

J Nelson Wright

Timothy P Mate

Eric Meier

David Thomas Stinson

Edward Scott Harshman

Hanson S Gifford, Iii

Eric Hadford

Robert N Meek

Mark E Deem

Daniel Reed Baker

Edward Joseph Vertatschitsch

Robin John Noel Coope

Lok Tin Lam

Lynn M Purdy

Keith Seiler

William T Mayo

Margo Gisselberg

Jack Goldberg

Matthew Allison Herron

Eric D Nielson

Kurt E Zublin

Roger Hildwein

James K Riley

Jeff Pelton

Parag Jitendra Parikh

Steven Paul Mertens

John Streeter

Carly Anderson Thaler

Fergus Quigley

Ryan Kempston Seghers

Stephen Phillips

Ryan Kaveckis

Rich Edelson

Tricia V Zeller

Hanson S Gifford

Edward Harshmann

Mark Deem

Hanson S Iii Gifford

A system and method can be used to denervate at least a portion of a bronchial tree. An energy emitter of an instrument is percutaneously delivered to a treatment site and outputs energy to damage nerve tissue of the bronchial tree. The denervation procedure can be performed without damaging non-targeted tissue. Minimally invasive methods can be used to open airways to improve lung function in subjects with COPD, asthma, or the like. Different sections of the bronchial tree can be denervated while leaving airways intact to reduce recovery times.

Non-invasive and minimally invasive denervation methods and systems for performing the same

Systems, delivery devices, and methods to treat to ablate, damage, or otherwise affect tissue. The treatment systems are capable of delivering a coolable ablation assembly that ablates targeted tissue without damaging non-targeted tissue. The coolable ablation assembly damages nerve tissue to temporarily or permanently decrease nervous system input. The system, delivery devices, and methods can damage tissue and manage scarring and stenosis.

Systems, apparatuses, and methods for treating tissue and controlling stenosis

Implantable devices for fixation of curved bone such as the pelvic ring pubic symphysis and acetabulum, and methods for the use of the devices are disclosed. The implantable devices are convertible between a flexible state and a rigid state, and include an elongate structure having a proximal bone interface, a main body, and a distal bone interface. In a flexible state, the devices may be inserted along, and conform to a curved pathway, and in the rigid state, the devices may support the mechanical loads required to fixate a fracture.

Shape adaptable intramedullary fixation device

Systems and methods for intermedullary bone fracture fixation are described herein. The fixation device includes a main body having a flexible state and a rigid state. The fixation device further includes a proximal interface coupled to a proximal end of the main body to anchor the fixation device to an exterior surface of the bone and a distal interface coupled to a distal end of the main body to anchor the fixation device to an interior cavity of the bone. The fixation device further includes a locking interface to configured to convert the main body from the flexible state to the rigid state.

Systems and methods for intermedullary bone fixation

Systems, assemblies, and methods to treat pulmonary diseases are used to decrease nervous system input to distal regions of the bronchial tree within the lungs. Treatment systems damage nerve tissue to temporarily or permanently decrease nervous system input. The treatment systems are capable of heating nerve tissue, cooling the nerve tissue, delivering a flowable substance that cause trauma to the nerve tissue, puncturing the nerve tissue, tearing the nerve tissue, cutting the nerve tissue, applying pressure to the nerve tissue, applying ultrasound to the nerve tissue, applying ionizing radiation to the nerve tissue, disrupting cell membranes of nerve tissue with electrical energy, or delivering long acting nerve blocking chemicals to the nerve tissue.

Systems, assemblies, and methods for treating a bronchial tree

The current invention features a rod screw for medical application that can be configured and used to fixate fracture of bones varying in shape and dimension, and treating maladies such as scoliosis, and securing an implanted device, to tissue such as bone. This is achieved by designing a flexible rod screw with a mechanism to lock the configuration in a rigid state. In an embodiment, a bone-fracture fixation device, such as a rod screw, includes a flexible body, a plurality of flexible members, and first and second interfaces. The flexible members are disposed longitudinally within the flexible body, such that the flexible body is rigid when the flexible members are fixed into position. And the first and second interfaces are respectively coupled to the flexible body, each of at least one of the first and second interfaces including a respective at least one hole each configured to receive a respective attachment member configured to engage a bone.

Bone-fixation device and system

A pulmonary treatment system includes a compact configuration for delivery to an airway of a patient. An energy delivery system of the pulmonary treatment system delivers ultrasound energy to target nerve tissue in or along an airway wall of the airway radially outward from surface tissue to reduce airway resistance in a downstream airway. The pulmonary treatment system may protect tissue in the airway wall of the airway located between the target nerve tissue and the ultrasound energy delivery system by a coolant system that may also act as a coupling fluid for the emitted ultrasound energy.

Systems, devices, and methods for treating a pulmonary disease with ultrasound energy

Systems and methods for treating a lung of a patient. One embodiment of a method comprises positioning a leadless marker in the lung of the patient relative to the target, and collecting position data of the marker. This method further comprises determining the location of the marker in an external reference frame outside of the patient based on the collected position data, and providing an objective output in the external reference frame that is responsive to movement of the marker. The objective output is provided at a frequency (i.e., periodicity) that results in a clinically acceptable tracking error. In addition, the objective output can also be provided at least substantially contemporaneously with collecting the position data used to determine the location of the marker.

Systems and methods for treating a lung of a patient using guided radiation therapy or surgery

Apparatuses and methods for implanting objects, such as a marker, in the lungs of patients. In one embodiment, a bronchoscopic catheter assembly for implanting an object in the lung of a patient includes a handle, a delivery catheter projecting outwardly from the handle, and a push wire contained within the catheter. In one aspect of this embodiment, the catheter can be configured to releasably hold a plurality of markers at a distal end. In another aspect of this embodiment, the push wire can be operably connected to the handle and axially moveable within the delivery catheter to eject the marker out of the catheter within the bronchi of the patient. In a further aspect of this embodiment, the marker can further include an anti-migration device associated with the marker for holding the marker in place once the marker is deployed in the bronchi. The anti-migration device can be integral with the marker or positioned proximate to the marker to prevent migration of the marker.

Apparatus and methods for implanting objects, such as a bronchoscopically implanting markers in the lung of patients

Growing community of inventors

Bellevue, WA, United States of America

Steven Charles Dimmer