Bayer Healthcare LLC

Ascensia Diabetes Care Holdings Ag

Miles Inc.

Bayer Corporation

Miles Laboratories, Inc.

Other

Ascensia Diagnostics Care Holdings Ag

Engelmann, Helmut

Charlton, Steven C.

Albarella, James P.

Reinsch, James W.

Warchal, Mary E.

Kurchacova, Elva

Steven C Charlton

Andrew J Edelbrock

Sung-Kwon Jung

Dijia Huang

Suny J George

Paul M Ripley

Hoi-Cheong Steve Sun

Jeffery S Reynolds

Mu Wu

Andrew J Dosmann

John P Creaven

Huan-Ping Wu

Frank W Wogoman

Narasinha C Parasnis

Amy H Chu

Russell J Micinski

Anne Tregoning Miller

Swetha Chinnayelka

Karen L Marfurt

Joseph E Perry

Yuan Wang

Qiang Fu

Igor Y Gofman

Eugene Randal Prais

Jun Chen

Xin Wang

Michael A Botta

Harris Lieber

Simin Yao

Steven Brian Harris

Gregory Stefkovic

Derek Lok

Tony Nguyen

Lin Chen

James P Albarella

Mihailo V Rebec

Allen J Brenneman

Matthew K Musho

Raymond L Yao

Dennis Slomski

Joseph L Moulton

Matthew A Schumann

Larry D Johnson

Paul R Hemmes

Matthew B Holzer

Qiong Li

Paul L Inman

Robert S Sams

Mirza Kokic

Steve Hoi-Cheong Sun

Gary J Johnson

Mary E Warchal

Robert P Hatch

Jiangfeng Fei

Serban F Peteu

Raeann Gifford

Bert Walter

Mark S Vreeke

Scott Hoover

Steve Sun

Catherine Ruetten

Roger L Fleming

Arthur L Lau

James W Reinsch

Anne T Miller

Kin F Yip

Joel M Blatt

Michael J Wilcox

Mary Ellen Warchal-Windham

Elva Kurchacova

Gary Johnson

Yingping Deng

James B Denton

Helmut Engelmann

Bruce A Flora

Karl-Heinz Hildenbrand

James J Venosky

Authur L Lau

Andy Edelbrock

Jeffrey S Reynolds

Arthur Ly Lau

Alan R Mccleary

Hoi-Wah Lok

In some aspects, an analyte sensor is provided for detecting an analyte concentration level in a bio-fluid sample. The analyte sensor has a base, a first electrode and a second electrode wherein a thermocouple portion is provided integral with the second electrode thereby enabling on-sensor temperature measurement capability. In some embodiments, two and only two electrical contact engagement portions are provided thereby simplifying electrical contact. Manufacturing methods and systems utilizing the analyte sensors are provided, as are numerous other aspects.

Temperature sensing analyte sensors, systems, and methods of manufacturing and using same

A biosensor system determines an analyte concentration of a biological sample using an electrochemical process without Cottrell decay. The biosensor system generates an output signal having a transient decay, where the output signal is not inversely proportional to the square root of the time. The transient decay is greater or less than the &#x2212;0.5 decay constant of a Cottrell decay. The transient decay may result from a relatively short incubation period, relatively small sample reservoir volumes, relatively small distances between electrode surfaces and the lid of the sensor strip, and/or relatively short excitations in relation to the average initial thickness of the reagent layer. The biosensor system determines the analyte concentration from the output signal having a transient decay.

Determining analyte concentration from variant concentration distribution in measurable species

A device and system for automatic handling of a sensor strip by a part of a meter that includes a sensor strip having a first section, a second section, and an intermediate section. The sensor strip includes at least a first opening about a first end thereof and a second opening about a second end thereof. A meter part includes a pair of pivoting catches configured to engage and grasp a sensor strip from a container containing a plurality of sensor strips. The sensor strip may thus be removed from a container for testing without need for manual handling of the strip by a user.

Bottled glucose sensor with no handling

A blood glucose monitor includes a can, a replaceable sensor cartridge that includes a frame, an upper spring disposed between the frame and the can, a case for housing the can and sealing the frame, a lower spring disposed between the can and the case, and a meter housing for sealing an upper portion of the frame. The can is capable of accepting the replaceable sensor cartridge. The frame of the removable cartridge has at least at least two walls defining a chamber for accepting a plurality of biosensors, and a bottom portion defining an opening and at least one sealing flange. The frame can further include a desiccant material capable of reducing humidity within the frame. The frame may be dimensioned such that an interference fit constrains the plurality of biosensors prior to inserting the frame within a blood glucose monitor.

Replaceable multistrip cartridge and biosenser meter

The present invention relates to a system, method, and meter for determining the concentration of an analyte in a fluid sample provided on a test strip. The meter () may include a body (), an optical reader (), and a test strip holder (). The body () has first () and second ends () and defines a longitudinal axis y extending between the first and second ends (). The optical reader () may be coupled to the body () and adapted to analyze the analyte on the test strip. The test strip holder () may be coupled to the body () and include first and second arms (). One of the optical reader () or the test strip holder () may be movable along the longitudinal axis of the body between a first position, in which the first and second arms () of the test strip holder () overlie the optical reader (), and a second position, in which the optical reader () extends beyond the first and second arms () of the test strip holder (). Such configuration allows to push the test strip against the optical reader (). Pins () are also disposed on the test strip holder () to grasp the extremities of the test strip and stretch said strip against the optical reader ().

Test strip meter with a mechanism for pushing the test strip against an optical reader

In some aspects, a device is provided having a member with a region of enhanced electrochemical activity. In one aspect, a sensor of enhanced electrochemical activity is provided for detecting an analyte concentration level in a bio-fluid sample. The sensor may include a sensor member of a semiconductor material wherein the sensor member has a surface region of enhanced electrochemical activity. In other aspects, the member may be made of semiconducting foam having a surface region of enhanced electrochemical activity. In some embodiments, the region may be thermally-induced. Manufacturing methods and apparatus are also provided, as are numerous other aspects.

Electrical devices with enhanced electrochemical activity and manufacturing methods thereof

Systems and methods for electrochemically oxidizing components of a test-sensor reagent prior to deposition on a test sensor comprise at least a first electrode and a second electrode for contacting the test-sensor reagent. The first electrode and the second electrode may have hollow interior portions for contacting the test-sensor reagent to produce a modified test-sensor reagent having a reduced background current.

Method for forming an optical test sensor

An architecture allows individual system components to be developed and tested individually, i.e., as distinct modules, and to be subsequently combined through standardized electrical and communication interfaces. Any combination of these modules can be implemented to form different products that provide any number of functions, such as an integrated system for monitoring a health condition and/or delivering a medication. The architecture also provides an approach for dynamically updating the product and offering its users the latest generation of technology even after the users have already purchased the product. In particular, the embodiments employ the communication interfaces to also provide connection to a remote network that can update or upgrade the product's software when the product is out in the field.

Architecture for field upgrade of a health monitoring system

Replaceable multistrip cartridge and biosensor meter

An integrated-testing system includes a meter, a lancing device and a storage case. The meter includes a housing, a display and a processor. The storage case holds the meter and the lancing device in a relatively fixed position to each other. The meter and the lancing device are maintained in the storage case in the relatively fixed position until a fluid sample is desired, at which time a first portion of the lancing device is advanced to a position external to the storage case to obtain the fluid sample and a second portion of the lancing device remains relatively fixed in the storage case while the fluid sample is obtained.

Integrated-testing system

In some aspects, an analyte sensor is provided for detecting an analyte concentration level in a biological fluid sample. The analyte sensor has a base including a top and bottom side, a lid, and an attachment member including one or more retention tabs coupled proximate the top side so that the analyte sensor can be grasped by the sensor's top side. Manufacturing methods and systems adapted to use and dispense the analyte sensors are provided, as are numerous other aspects.

Analyte sensors and systems including retention tab and methods of manufacturing same

A test sensor includes a body, a first conductive trace, a second conductive trace, and a third conductive trace. The body includes a first region that has a fluid-receiving area, a second region separate from the first region, and a first temperature sensing interface disposed at or adjacent to the fluid-receiving area. The fluid-receiving area receives a sample. The first trace is disposed on the body, and at least a portion of the first trace is disposed in the first region. The second and third traces are disposed on the body. The third trace extends from the first to the second regions. The third trace is connected to the first trace at the first temperature sensing interface. The third trace includes a different material than the first trace. A first thermocouple is formed at the first temperature sensing interface. The thermocouple provides temperature data to determine an analyte concentration.

System and apparatus for determining temperatures in a fluid analyte system

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Osceola, IN, United States of America

Steven C Charlton