Miroculus Inc.

Sandia Corporation

National Technology & Engineering Solutions of Sandia, LLC

Integra Biosciences Ag

Steven Branda

Ronald Francis Renzi

Mais Jehan Jebrail

Kamlesh D Patel

Scott M Ferko

James L Van De Vreugde

Victoria A VanderNoot

Stanley Alan Langevin

Todd W Lane

Kelly Porter Williams

Zachary Bent

Raga Krishnakumar

Described herein are digital microfluidic (DMF) devices and corresponding methods for managing reagent solution evaporation during a reaction. Reactions on the DMF devices described here are performed in an air or gas matrix. The DMF devices include a means for performing reactions at different temperatures. To address the issue of evaporation of the reaction droplet especially when the reaction is performed at higher temperatures, a means for introducing a replenishing droplet has been incorporated into the DMF device. A replenishing droplet is introduced every time when it has been determined that the reaction droplet has fallen below a threshold volume. Detection and monitoring of the reaction droplet may be through visual, optical, fluorescence, colorimetric, and/or electrical means.

Evaporation management in digital microfluidic devices

The present invention relates, in part, to engineered viruses (e.g., engineered phages), phage cocktails, and methods of producing and/or identifying viruses for targeting pathogenic bacteria.

Therapeutic phages and methods thereof

A system for enhancing a nucleic acid sample may include a one pump, a denaturing chamber; a microfluidic hydroxyapatite chromatography device configured for performing hydroxyapatite chromatography on the nucleic acid sample, a sample collector, and tubing connecting the pump with the denaturing chamber, the hydroxyapatite chromatography device and the sample collector such that the pump may be used to move the nucleic acid sample from the denaturing chamber to the hydroxyapatite chromatography device and then to the sample collector.

Multiplexed microfluidic approach for nucleic acid enrichment

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Livermore, CA, United States of America

Steven Branda