Advanced Bio Prosthetic Surfaces, Ltd.

Abps Venture One, Ltd.

The University of Texas System

Advanced Bio Prosthetic Surfaces, Ltd., a Wholly Owned Subsidiary of Palmaz Scientific, Inc.

Vactronix Scientific, Llc.

Abps Venture One, Ltd., a Wholly Owned Subsidiary of Palmaz Scientific, Inc.

Steven Bailey

Christopher T Boyle

Christopher E Banas

Julio C Palmaz

Denes Marton

Chandra Mauli Agrawal

J Jordan Massey Kaufmann

Eugene A Sprague

Roger W Wiseman

Mauli Agrawal

Jodie L Polan

Cristina Fuss

Peter Starr

Roger Wiseman

Christina Fuss

A thin-film, diaphragm based device is disclosed which can be used to perform an array of sensing and actuating operations where a very thin profile is desired, such as in millimeter, micrometer, or nanometer tight spaces.

Devices and methods for parameter measurement

Implantable in vivo sensors used to monitor physical, chemical or electrical parameters within a body. The in vivo sensors are integral with an implantable medical device and are responsive to externally or internally applied energy. Upon application of energy, the sensors undergo a phase change in at least part of the material of the device which is then detected external to the body by conventional techniques such as radiography, ultrasound imaging, magnetic resonance imaging, radio frequency imaging or the like. The in vivo sensors of the present invention may be employed to provide volumetric measurements, flow rate measurements, pressure measurements, electrical measurements, biochemical measurements, temperature, measurements, or measure the degree and type of deposits within the lumen of an endoluminal implant, such as a stent or other type of endoluminal conduit. The in vivo sensors may also be used therapeutically to modulate mechanical and/or physical properties of the endoluminal implant in response to the sensed or monitored parameter.

Method of using an in vivo sensor having differential material properties

A device for treating a damaged tissue includes an expandable scaffold positionable in a portion of a luminal tissue structure of a mammal; and maintained via stent technology, wherein the scaffold is comprised of electrospun fibers composed of a biodegradable compound. The scaffold serves as a temporary template that allows the tissue to be rebuilt.

Scaffold system for tissue repair

A metal balloon catheter having a main tubular body, a metal balloon proximate a distal end of the main tubular body, a central annulus extending along an entire longitudinal aspect of the catheter for accommodating a guidewire therethrough and an inflation annulus adjacent the central annulus which extends along the longitudinal axis of the main tubular body and terminates in fluid flow communication with an inflation chamber of the metal balloon. The metal balloon catheter may be either unitary integral metal catheter in which the main tubular body and the balloon are fabricated of metal, or it may consist of a polymeric main tubular body and a metal balloon.

Balloon catheter having metal balloon and method of making same

Implantable in vivo sensors used to monitor physical, chemical or electrical parameters within a body. The in vivo sensors are integral with an implantable medical device and are responsive to externally or internally applied energy. Upon application of energy, the sensors undergo a phase change in at least part of the material of the device which is then detected external to the body by conventional techniques such as radiography, ultrasound imaging, magnetic resonance imaging, radio frequency imaging or the like. The in vivo sensors of the present invention may be employed to provide volumetric measurements, flow rate measurements, pressure measurements, electrical measurements, biochemical measurements, temperature, measurements, or measure the degree and type of deposits within the lumen of an endoluminal implant, such as a stent or other type of endoluminal conduit.

In vivo sensor and method of making same

This invention relates to prosthetic cardiac and venous valves and a single catheter device and minimally invasive techniques for percutaneous and transluminal valvuloplasty and prosthetic valve implantation.

Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof

Guidewires and thin-film catheter-sheaths, fabricated using vacuum deposition techniques, which are monolayer or plural-layer members having ultra-thin wall thicknesses to provide very-low profile delivery assemblies for introduction and delivery of endoluminal devices.

Guidewires and thin film catheter-sheaths and method of making same

The present invention consists of an implantable structural element for in vivo controlled delivery of bioactive active agents to a situs in a body. The implantable structural element may be configured as an implantable prosthesis, such as an endoluminal stent, cardiac valve, osteal implant or the like, which serves a dual function of being prosthetic and a carrier for a bioactive agent. Control over elution of the bioactive agents occurs through a plurality of cantilever-like cover members which prevent drug elution until an endogenous or exogenous stimulus causes the cover members to open and permit drug elution.

Device for in vivo delivery of bioactive agents and method of manufacture thereof

An endoluminal stent composed of a plurality of first structural elements arrayed to form the circumference of the stent and extending along the longitudinal axis of the stent, and a plurality of second structural elements that interconnect adjacent pairs of first structural elements. The plurality of first structural elements have either a linear shape or a generally sinusoidal configuration with either a regular or irregular periodicity or regions of regular and regions of irregular periodicity between the peaks and troughs of the pattern, with the peaks and troughs projecting from the first structural elements in the circumferential axis. The plurality of second structural elements are generally linear or sinusoidal-shaped members which interconnect an apex of a peak of one of the plurality of first structural elements with an apex of a valley of a second and adjacent one of the plurality of first structural elements. Each of the plurality of second structural elements are generally oriented parallel to the circumferential axis of the stent.

Growing community of inventors

San Antonio, TX, United States of America

Steven Bailey