Steven A Benner

Zunyi Yang

Myong Jung Kim

This invention provides molecules that bind to and/or chemically transform a preselected target such as a protein molecule, where the molecules contain one or more 'non-standard' nucleotides. These are nucleotide analogs that, when incorporated into oligonucleotides (DNA or RNA, collectively NA), present a pattern of hydrogen bonds that is different from the pattern presented by adenine, guanine, cytosine, and uracil or thymidine.

Binding and catalytic molecules built from expanded DNA

This invention covers processes that amplify multiple DNA and RNA targets, solving the 'multiplexed PCR problem', as well as supporting isothermal amplification and delivering other capabilities in multiplexed molecular analysis. It uses inventive DNA analogs.

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Gainesville, FL, United States of America

Steven A Benner