Koninklijke Philips Corporation N.v.

Flow Forward Medical, Inc.

Artio Medical, Inc.

Steve Woodard

Barrett Hutto

F Nicholas Franano

Howard M Loree, Ii

Geoff Tansley

Asheesh Divetia

Matthias Hamsch

Joachim Kahlert

Michel Paul Barbara Van Bruggen

Chantal Nathalie Van Den Broek

Ruth Beeby

J Scott Richardson

Antonius Adrianus Petrus Schudelaro

Howard M Loree Ii

Howard M Loree

The present disclosure relates to a rotary blood pump system. The rotary blood pump system may comprise an inflow conduit, an outflow conduit, a control system, and a power source. The present disclosure further relates to various inflow conduit assemblies comprising a conduit tip comprised of metal or polymer having an undulating opening surface that provides improved blood flow and washing properties while minimizing regions susceptible to stagnation, and optionally a resilient tip-protecting cage structure that reduces the risk of conduit tip suction events and suction-related injury of the wall of adjacent blood vessels or other blood containing structures. The present disclosure further relates to various outflow conduit assemblies with a conduit tip comprised of metal or polymer wherein the cross-sectional area of the lumen of the conduit or conduit tip is reduced to generate a localized jet-like fluid flow in a blood vessel segment adjacent to the conduit tip.

Conduit tips and systems and methods for use

The present invention relates to a rotary blood pump with a double pivot contact bearing system with an operating range between about 50 mL/min and about 1500 mL/min, wherein the force on the upper bearing is less than 3N during operating speeds up to 6000 rpm. The rotary blood pump is part of a blood pump system that includes blood conduit(s), a control system with optional sensors, and a power source. Embodiments of the present invention may include elements designed to increase the length of time the rotary blood system can operate effectively in vivo, including wear resistant bearing materials, a rotor back plate for magnetic attraction of the rotor to reduce bearing pivot bearing forces and wear, a rotor size and shape and a bearing gap that combine to create a hydrodynamic bearing effect and reduce bearing pivot bearing forces and wear, improved intravascular conduits with increased resistance to thrombosis, conduit insertion site cuffs to resist infection, and conduit side ports amenable to the easy insertion of guidewire and catheter-based medical devices to treat conduits and related blood vessels to maintain blood pump system function over time.

Blood pump systems and methods

A tongue advancer assembly for a tongue manipulation system includes a core mount and a tongue advancer for coupling to the core mount. The core mount includes a connection rod coupling for coupling the tongue advancer assembly to a distal end of a connection rod.

Tongue advancer assembly for a tongue manipulation system

A tongue advancer implant () or removal () tool for a tongue manipulation system comprising: a loading mechanism configured to enable the loading of an implant or removal assembly; a propulsion element configured to be charged; a release mechanism configured to permit the propulsion element to propel the implant or removal assembly from the implant or removal tool.

Tongue advancer implant or removal tool for a tongue manipulation system

A connection tool for a tongue manipulation system includes a connector configured to be coupled to a tongue advancer tether, a connection tool body, and a separable removal cannula part. The separable removal cannula part is configured to follow a tongue advancer tether line in order to enable a removal sleeve located at least partially within the separable removal cannula part to contact the tongue advancer. The separable removal cannula part is configured to be separated from the connection tool body following the removal sleeve contacting the tongue advancer and to expose a proximal end of the removal sleeve.

Tools for a tongue manipulation system

The present invention relates to a rotary blood pump with a double pivot contact bearing system with an operating range between about 50 mL/min and about 1500 mL/min, wherein the force on the upper bearing is less than 3 N during operating speeds up to 6000 rpm. The rotary blood pump is part of a blood pump system that includes blood conduit(s), a control system with optional sensors, and a power source. Embodiments of the present invention may include elements designed to increase the length of time the rotary blood system can operate effectively in vivo, including wear resistant bearing materials, a rotor back plate for magnetic attraction of the rotor to reduce bearing pivot bearing forces and wear, a rotor size and shape and a bearing gap that combine to create a hydrodynamic bearing effect and reduce bearing pivot bearing forces and wear, improved intravascular conduits with increased resistance to thrombosis, conduit insertion site cuffs to resist infection, and conduit side ports amenable to the easy insertion of guidewire and catheter-based medical devices to treat conduits and related blood vessels to maintain blood pump system function over time.

The present invention relates to a rotary blood pump with a double pivot contact bearing system with an operating range between about 50 mL/min and about 1500 mL/min. The rotary blood pump is part of a blood pump system that includes blood conduit(s), a control system with optional sensors, and a power source. Embodiments of the present invention may include elements such as wear resistant bearing materials, a rotor back plate for magnetic attraction of the rotor to reduce bearing pivot bearing forces and wear, a rotor size and shape and a bearing gap that combine to create a hydrodynamic bearing effect and reduce bearing pivot bearing forces and wear, improved intravascular conduits with increased resistance to thrombosis, conduit insertion site cuffs to resist infection, and conduit side ports amenable to the easy insertion of guidewire and catheter-based medical devices.

The present disclosure relates to a rotary blood pump with a double pivot contact bearing system with an operating range between about 50 mL/min and about 1500 mL/min, wherein the force on the upper bearing is less than 3N during operating speeds up to 6000 rpm. The disclosure also relates to a method of using a blood pump system for persistently increasing the overall diameter and lumen diameter of peripheral veins and arteries by persistently increasing the speed of blood and the wall shear stress in a peripheral vein or artery for period of time sufficient to result in a persistent increase in the overall diameter and lumen diameter of the vessel.

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Los Gatos, CA, United States of America

Steve Woodard