Baxter International Inc.

Steve Pearson

Clinton V Kopp

Brian D Zdeb

Glenn L Slater

Rao Chilamkurti

Jeremy C Wright

Thomas E Needham

An apparatus is provided for the safe, passive reconstruction of a drug or other beneficial agent, without requiring manual reconstitution steps. The apparatus includes a housing, preferably having a receptacle 'in-line' in an administration set and forming part of an intravenous delivery system, and a cartridge adapted for receiving a beneficial agent or beneficial agent and carrier. The cartridge is plugged into the receptacle to initiate reconstitution of the agent. The apparatus creates first and second delivery modes, in which the delivery rate of the agent to a patient is independent from and dependent upon, respectively, the fluid flow rate through the intravenous delivery system.

Drug delivery apparatus and method preventing local and systemic toxicity

A housing is provided for insertion in an intravenous delivery system including a fluid source and a fluid conduit. The housing is adapted for receiving a beneficial agent to be mixed with fluid flowing through the fluid conduit. The beneficial agent is reconstituted within the housing, eliminating the need for manual reconstitution. The housing may comprise a separate receptacle and cartridge in which the receptacle is manufactured 'in-line' in an administration set and the cartridge is adapted for receiving a beneficial agent. In one embodiment of the invention, the cartridge is a standard drug vial.

Housing enabling passive mixing of a beneficial agent with a diluent

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Ingleside, IL, United States of America

Steve Pearson