Neurelis, Inc.

Questcor Pharmaceuticals, Inc.

Hale Biopharma Ventures, LLC

Rhode Island Hospital

Mallinckrodt Ard IP Limited

Aegis Therapeutics, LLC

Steve Cartt

Edward T Maggio

David Medeiros

Mark Mitchnick

Garry Thomas Gwozdz

David F Hale

Andrew L Loxley

Rujun Gong

Andrew Loxley

David Young

James Knight

Patrice Becker

The invention relates to pharmaceutical compositions comprising one or more benzodiazepine drugs for nasal administration, methods for producing and for using such compositions.

Administration of benzodiazepine compositions

Provided herein are methods for prophylactic treatment of renal disorders comprising administration of adrenocorticotropic hormone (ACTH), or fragment, analog, complex or aggregate thereof, or any combination thereof, to an individual suspected of having, predisposed to, or at risk of developing a renal disorder.

ACTH prophylactic treatment of renal disorders

Provided herein are methods of treatment of acute respiratory distress syndrome comprising administration of adrenocorticotropic hormone (ACTH). or fragment, analog, complex or aggregate thereof, or any combination thereof, to an individual in need thereof.

ACTH for treatment of acute respiratory distress syndrome

Multimodal particulate formulations of medicaments and methods for their use, e.g. by nasal or pulmonary administration for the treatment of various medical conditions, are provided.

Multimodal particulate formulations

Disclosed herein is a method for treating a patient with Quazepam that reduces the risk of an adverse interaction between the Quazepam and drug that is a substrate of the cytochrome P450 enzyme isoform 2B6 (CYP2B6 substrate drug), e.g., Bupropion. The method includes determining if the patient to be treated with Quazepam is being treated with a CYP2B6 substrate drug, and prescribing or treating the patient with Quazepam based on the determination.

Methods for reducing the risk of an adverse drug interaction in a patient suffering from insomnia

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Union City, CA, United States of America

Steve Cartt