Essenlix Corporation

Princeton University

Other

University of Minnesota

Nanonex Corporation

Nanoopto Corporation

Stephen Y Chou

Wei Ding

Ji Qi

Yufan Zhang

Hua Tan

Jun Tian

Wu Chou

Ji Li

Wei Zhang

Han Cao

Robert H Austin

Jonas O Tegenfeldt

Lin Hu

Yuecheng Zhang

Mingquan Wu

Zhaoning Yu

Xing Li

Xiaogan Liang

Wendi Li

Hongbing Li

Liang-Cheng Zhou

Wei Dong

Linshu Kong

Ying Wang

Wei E Wu

Yixing Liang

Lei Zhuang

Qiangfei Xia

Shufeng Bai

Yu Sun

Shengjian Cai

Jian Jim Wang

Christopher Fred Keimel

Lei Chen

Parikshit A Deshpande

Anguel N Nikolov

Can Peng

Mingtao Li

Colby Steere

Bo Cui

Jonas O Tagenfeldt

Fei Ding

Lingjie Guo

Effendi Leobandung

Jia Peng

Rich Zhaoning Yu

Jim Jiam Wong

Allan S P Chang

Allan Chang

Leonard F Pease, Iii

William B Russel

Mingtao (Gary) Li

He Gao

Haixlong Ge

Zengli Fu

Cao,han

Jonas Tegenfeldt

Among other things, the present disclosure is related to devices and methods for containing a liquid sample between two plates.

Containing a liquid sample

Among other things, the disclosure of the present invention is related to make pathology and cytology faster, better and lower cost. The present invention also related to rapid intracellular assay.

Rapid pathology/cytology without wash

Disclosed is an apparatus and method for imaging: a side-view of a object on a surface, a Contact Angle of a liquid object, the color of an object, or combinations thereof.

Color imaging based assay

Among other things, the present invention is related to devices and methods for improving optical analysis of a thin layer of a sample sandwiched between containing between two plates.

Optical transmission sample holder and analysis, particularly for hemoglobin

One aspect of the present invention is to provide the device and methods for performing an assay that uses the multiplexing of sample thicknesses on the same plate. The sample thickness multiplexing can offer many information that is unavailable in using a single sample thickness.

Assay using sample thickness multiplexing

The present invention provides devices, systems, and methods for rapid and easy-to-use in sample thermal cycling or temperature changes for the facilitation of reactions such as but not limited to PCR.

Assay with rapid temperature change

A multiplex assay device including: a separation structure on a first plate; and a sample contact area on the surface of the first plate. Also disclosed is a method for fabricating a multiplex assay, including: making a reagent into a non-liquid reagent particle; creating a well on a sample contact area of a plate of a Q-card two plate sample card; and dropping one or more of the non-liquid reagent particles into at least one well.

Multiplex assays using separation structure and well structure

Among other things, the present invention is related to devices and methods for improving optical analysis of a thin layer of a sample sandwiched between two plates.

A multi-mode illumination system, including: a first illumination module; a second illumination module; and a third illumination module, as disclosed herein.

Multi-mode illumination system

A microscopy imaging system and methods for improving an assaying of a sample is disclosed.

Compact optical system for improving sample imaging

Disclosed are devices and methods for analyzing an analyte, such as white blood cells in liquid samples.

Cell analysis in body fluids, particularly blood using a sample card with multiple spacer sets having at least two distinct substantially uniform heights

The present invention is related to the field of bio/chemical sampling, sensing, assays and applications. Particularly, the present invention is related to how to make the sampling/sensing/assay become simple to use, fast to results, highly sensitive, easy to use, using tiny sample volume (e.g., 0.5 μL or less), operated by a person without any professionals, reading by mobile-phone, or low cost, or a combination of them.

Device and system for analyzing a sample, particularly blood, as well as methods of using the same

The present invention provides QMAX based devices, kits, and methods for rapid, easy to use, and/or inexpensive detection of assaying.

QMAX assay and applications (II)

Disclosed is an optical system for interrogating a sample, an optical system for measuring the spectrum of a beam of light, an optical system for measuring the spectrum of two beams of light, a compact imaging-based sensor or sensors, and combinations thereof.

Compact imaging-based sensors

The present disclosure relates to devices, apparatus and methods of improving the accuracy of image-based assay, that uses imaging system having uncertainties or deviations (imperfection) compared with an ideal imaging system. One aspect of the present invention is to add the monitoring marks on the sample holder, with at least one of their geometric and/optical properties of the monitoring marks under predetermined and known, and taking images of the sample with the monitoring marks, and train a machine learning model using the images with the monitoring mark.

Efficient training and accuracy improvement of imaging based assay

Growing community of inventors

Princeton, NJ, United States of America

Stephen Y Chou