Novartis Finance Corporation

Ciba-geigy Corporation

Novartis Corporation

Syngenta Investment Corporation

Syngenta Investments, Inc.

Stephen V Evola

Michael G Koziel

Gregory W Warren

Nalini M Desai

Martha S Wright

Erik M Dunder

Karen L Launis

Gary M Pace

John L Dawson

Janet L Suttie

Cindy G Bowman

Kelly S Lewis

Steven J Rothstein

Lyle Dean Crossland

Vance C Kramer

Ellis J Merlin

Nadine B Carozzi

Vance Cary Kramer

Moez Rajabali Meghji

Annick Jeanne De Framond

Bruce Wayne Skillings

James O Linder

Robert L Miller

Christopher P Clucas

Francis P Cammack

Alan W Mousel

Francis E Cassagne

Albert R Hornbrook

Andreas H Tanner

Gilles Pollini

Terry Ray Colbert

Nadine G Carozzi

Methods for transformation of maize with nucleic acid sequences of interest are disclosed. The method involves subjecting immature zygotic embryos or Type I callus to high velocity microprojectile bombardment. The method is capable of producing transformed maize lines of commercial importance and their hybrid combinations.

Method of producing transgenic maize using direct transformation of commercially important genotypes

DNA sequences optimized for expression in plants are disclosed. The DNA sequences preferably encode for an insecticidal polypeptides, particularly insecticidal proteins from,. Plant promoters, particular tissue-specific and tissue-preferred promoters are also provided. Additionally disclosed are transformation vectors comprising said DNA sequences. The transformation vectors demonstrate high levels of insecticidal activity when transformed into maize.

Synthetic DNA sequences having enhanced insecticidal activity in maize

DNA sequences optimized for expression in plants are disclosed. The DNA sequences preferably encode for an insecticidal polypeptides, particularly insecticidal proteins from Bacillus thuringiensis. Plant promoters, particular tissue-specific and tissue-preferred promoters are also provided. Additionally disclosed are transformation vectors comprising said DNA sequences. The transformation vectors demonstrate high levels of insecticidal activity when transformed into maize.

Synthetic DNA sequence having enhanced insecticidal activity in maize

Nucleic acid promoter fragment isolated from a plant tryptophan synthase

Synthetic DNA sequence having enhanced activity in maize

Four new strains of Bacillus thuringiensis are disclosed which are active against Coleoptera. The novel strains are identified through PCR technology using mixtures of carefully selected oligonucleotide primers that aid in the prediction of insect toxicity profile for the proteins produced by the strains.

Method for characterizing insecticidal properties of unknown bacillus

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Apex, NC, United States of America

Stephen V Evola