Other

University of Illinois

Reebok International Limited

Gentherm Gmbh

Novasentis, Inc.

Kemet Electronics Corporation

Musarubra US LLC

Cryomedics, Inc.

K9 Scrub Club Inc.

Stephen Scott Davis

David R Hall

Joshua Larsen

Jared Reynolds

Kaitlyn C Gray

Martin D Burke

David M Knapp

Justin Robert Struble

Ian Dailey

Brice E Uno

Pulin Wang

Nagarjuna Palyam

Lon Edward Bell

Christophe Ramstein

Mauro Pezzato

Li Jiang

John Walter LaGrandeur

Brian C Zellers

John Loiars

Richard W Ducharme

M Fabrice Domingues Dos Santos

Shihai Zhang

Dan Allen

Terrece Pearman

Jared Miller Wagner

Mark Levatich

Brian Keoki Andrus

Aden K Andrus

Megen E Kepas

Austen W Schulz

Charles Jason OHara

Provided are certain derivatives of amphotericin B (AmB) characterized by reduced toxicity and retained anti-fungal activity. Certain of the derivatives are C16 urea derivatives of AmB. Certain of the derivatives are C3, C5, C8, C9, C11, C13, or C15 deoxy derivatives of AmB. Certain of the derivatives include C3′ or C4′ modifications of the mycosamine appendage of AmB. Also provided are methods of making AmB derivatives of the invention, pharmaceutical compositions comprising AmB derivatives of the invention, and methods of use of AmB derivatives of the invention.

Amphotericin B derivatives with improved therapeutic index

A computing system including a processor and a memory, which includes a first memory region operating as a kernel space and a second memory region operating as a user space. Maintained within the kernel space, a first logic unit receives a notification identifying a newly created thread and extracts at least meta-information associated with the newly created thread. Maintained within the user space, a second logic unit receives at least the meta-information associated with the newly created thread and conducts analytics on at least the meta-information to attempt to classify the newly created thread. An alert is generated by the second logic unit upon classifying the newly created thread as a cyberattack associated with a malicious position independent code execution based at least on results of the analytics associated with the meta-information associated with the newly created thread.

System and method for identifying and mitigating cyberattacks through malicious position-independent code execution

Electromechanical polymer (EMP) actuators are used to create haptic effects on a user interface deface, such as a keyboard. The keys of the keyboard may be embossed in a top layer to provide better key definition and to house the EMP actuator. Specifically, an EMP actuator is housed inside an embossed graphic layer that covers a key of the keyboard. Such a keyboard has a significant user interface value. For example, the embossed key provides the tactile effect of the presence of a key with edges, while allowing for the localized control of haptic vibrations. For such applications, an EMP transducer provides high strains, vibrations or both under control of an electric field. Furthermore, the EMP transducer can generate strong vibrations. When the frequency of the vibrations falls within the acoustic range, the EMP transducer can generate audible sound, thereby functioning as an audio speaker.

Thin profile user interface device and method providing localized haptic response

A system for conditioning and moving a fluid can include a thermoelectric device comprising a first side and a second side, the first side configured to heat or cool the fluid with electrical current applied to the thermoelectric device. The system can include a fluid conduit configured to allow a fluid to flow therein and to transfer the fluid into being in thermal communication with the thermoelectric device. The system can include a flow control device in fluid communication with the thermoelectric device, the flow control device configured to direct the fluid in the fluid conduit with respect to the thermoelectric device. The system can include a flapper valve configured to move relative to the thermoelectric device to at least partially block flow of the fluid through a portion of the fluid conduit.

Thermal management system including flapper valve to control fluid flow for thermoelectric device

Provided are certain derivatives of amphotericin B (AmB) characterized by reduced toxicity and retained anti-fungal activity. Certain of the derivatives are C16 urea derivatives of AmB. Certain of the derivatives are C3, C5, C8, C9, C11, C13, or C15 deoxy derivatives of AmB. Certain of the derivatives include C3' or C4&#x2032; modifications of the mycosamine appendage of AmB. Also provided are methods of making AmB derivatives of the invention, pharmaceutical compositions comprising AmB derivatives of the invention, and methods of use of AmB derivatives of the invention.

A cattle curtain utilizing a wicking action to displace concentrated insecticide to be wiped on animals as they pass through an animal pathway. The cattle curtain includes a reservoir body for holding the concentrated insecticide. A series of ropes is secured within the reservoir body, and the series of ropes is secured through fittings, whereby a metal pin is inserted through each rope. A valve disposed on top of the reservoir body to control flow of the concentrated insecticide into the series of ropes.

Cattle curtain

The present invention is directed to a toilet that includes a liquid level sensor on the surface of a flush jet fill tube. The liquid level sensor is a noncontact electrical impedance sensor that is an electrical capacitor. The capacitor may be used alone or with other volume sensors to detect volume of materials added to a toilet bowl. Some embodiments include a processor which records data and provides reports that may be clinically useful to assess the user's health status. The temporal nature of the liquid level sensor measurements is particularly useful because urination or defecation may be measured over time. Not only are total volumes detected but rates at which waste is deposited into the toilet during the entire excretion event are detected. These measurements are particularly useful in assessing certain health conditions.

Toilet with flush jet fill tube flow meter

The present invention relates to a urine specimen capture device comprising a narrow slit disposed on a surface exposed to urine that retains a portion of the urine specimen.

Urine specimen capture slit

The present invention relates to a urine specimen capture device comprising a capture bowl to capture a urine specimen, a mounting frame connected to the capture bowl to support the capture bowl within a toilet bowl and one or more flush water capture flange for capturing flush water emitted from a toilet bowl rim during a toilet flush cycle and diverting the flush water to the capture bowl to rinse the capture bowl of the urine specimen.

Urine hat flush water capture device

The urine specimen capture device includes a capture bowl for collecting a urine specimen, a mounting frame for supporting the capture bowl within a toilet bowl, and an analytic device connected to the capture bowl to analyze a property of the urine specimen in the capture bowl. The capture bowl includes a capture flange for capturing flush water discharged from a toilet bowl.

Urine specimen capture device with a capture flange

In certain embodiments, a battery thermal management system includes at least one battery, at least one thermoelectric device in thermal communication with the at least one battery, and a conduit comprising an inlet configured to allow a working fluid to enter and flow into the conduit and into thermal communication with the at least one thermoelectric device. The conduit further comprises an outlet configured to allow the working fluid to exit and flow from the conduit and away from being in thermal communication with the at least one thermoelectric device. The battery thermal management system can further include a first flow control device which directs the working fluid through the inlet of the conduit and a second flow control device which directs the working fluid through the outlet of the conduit. The first flow control device and the second flow control device are each separately operable from one another.

Thermoelectric-based battery thermal management system

The present invention relates to a urine specimen capture device comprising a capture bowl for collecting a urine specimen, a mounting frame for supporting the capture bowl within a toilet bowl, and an analytic device connected to the capture bowl to analyze a property of the urine specimen in the capture bowl.

Urine specimen capture and analysis device

Growing community of inventors

Payson, UT, United States of America

Stephen Scott Davis