Government of the United States of America, as Represented by the Secretary of Commerce

Stephen Russek

John M Moreland

Elizabeth Mirowski

William Rippard

Michael Schneider

Matthew Pufall

Karl Francis Stupic

A hyperpolarization micro-magnetic resonance imager for three-dimensional imaging of a biological composition with cellular resolution includes a hyperpolarizer source, hyperpolarizer transmission line, an NMR console, a nuclear magnetic resonance tuned circuit, an imaging cell, a magnet, a gradient-shim coil, a Hall probe and thermometer, and a printed circuit board.

Hyperpolarization micro-magnetic resonance imager and three-dimensional imaging of a biological composition with cellular resolution

A neural member includes: an axonal superconducting electrode; a dendritical superconducting electrode disposed opposing the axonal superconducting electrode; a synaptic barrier interposed between the axonal superconducting electrode and the dendritical superconducting electrode and including a plurality of magnetic clusters, the synaptic barrier being a tunable magnetic barrier between an ordered magnetic state and a disordered magnetic state such that: the axonal superconducting electrode, the dendritical superconducting electrode, and the synaptic barrier are arranged as a dynamically reconfigurable Josephson junction.

Neural member, neural network, and neurological memory

Arrays of spin-valve elements that can be selectively activated to trap, hold, manipulate and release magnetically tagged biological and chemical particles, including molecules and polymers. The spin-valve elements that can be selectively activated and deactivated by applying a momentary applied magnetic field thereto. The spin valve element array can be used for selectively sorting and transporting magnetic particles one particle at a time within the array. As the magnetically tagged particles are held by the spin-valve elements, application of an auxiliary magnetic field can be used to apply tension or torsion to the held particles or to move, e.g. rotate, the trapped particles. The arrays of spin-valve elements can be used in a variety of applications including drug screening, nucleic acid sequencing, structural control and analysis of RNA/DNA and proteins, medical diagnosis, and magnetic particle susceptibility and size homogenization for other medical applications.

Microfluidic platform of arrayed switchable spin-valve elements for high-throughput sorting and manipulation of magnetic particles and biomolecules

Arrays of spin-valve elements that can be selectively activated to trap, hold, manipulate and release magnetically tagged biological and chemical particles, including molecules and polymers. The spin-valve elements that can be selectively activated and deactivated by applying a momentary applied magnetic field thereto. The spin valve element array can be used for selectively sorting and transporting magnetic particles one particle at a time within the array. As the magnetically tagged particles are held by the spin-valve elements, application of an auxiliary magnetic field can be used to apply tension or torsion to the held particles or to move, e.g. rotate, the trapped particles. The arrays of spin-valve elements can be used in a variety of applications including drug screening, nucleic acid sequencing, structural control and analysis of RNA/DNA and protiens, medical diagnosis, and magnetic particle susceptibility and size homogenization for other medical applications.

Growing community of inventors

Louisville, CO, United States of America

Stephen Russek