Arch Biosurgery, Inc.

Myomo, Inc.

Other

Stephen Richard Kelly

Rutledge Ellis-Behnke

Terrence Norchi

Samuel Kesner

Andrew Harlan

Gene Tacy

Terrence W Norchi

James J Lockshaw

Randall B Walker

John Kaiser, Jr

A powered orthotic device for use with a limb having at least two joints includes at least two brace sub-assemblies. The first brace sub-assembly includes a first powered actuator assembly that receives a first sensor signal from a sensor selected from a group consisting of an electromyographic sensor, an inertial measurement unit, and combinations thereof. The first powered actuator assembly applies a first force for driving sections positioned with respect to a first joint to move relative to one another. The second brace sub-assembly includes a second powered actuator assembly that is configured to receive a second sensor signal from a sensor selected from a group consisting of an electromyographic sensor, an inertial measurement unit, and combinations thereof. The second powered actuator assembly applies a second force for driving sections positioned with respect to a second joint to move relative to one another. The first force and the second force are based on the first sensor signal or the second sensor signal.

Powered orthotic device and method of using same

A powered orthotic device for use with a limb having at least two joints includes at least two brace sub-assemblies. The first brace sub-assembly includes a first powered actuator assembly that receives a first sensor signal from an electromyographic sensor. The first powered actuator assembly applies a first force for driving sections positioned with respect to a first joint to move relative to one another. The second brace sub-assembly includes a second powered actuator assembly that is configured to receive a second sensor signal from a sensor selected from a group consisting of an electromyographic sensor, an inertial measurement unit, and combinations thereof. The second powered actuator assembly applies a second force for driving sections positioned with respect to a second joint to move relative to one another. The second force is based on the first sensor signal or the second sensor signal.

A method has been developed of preventing or limiting formation of adhesions by administering to a site in need thereof, in the absence of or after bleeding or leakage of fluid has been substantially stopped, a self-assembling material which forms a barrier to formation of adhesions. In certain embodiments, the self assembling materials are peptidomimetics, nucleotidomimetics, di- and triblock copolymers, N-alkylacrylamides, or dendrimers. These materials are also useful in a method for regeneration or repair of tissue or cells forming tissue.

Compositions for prevention of adhesions and other barrier applications

A method has been developed of preventing or limiting formation of adhesions by administering to a site in need thereof, in the absence of or after bleeding or leakage of fluid has been substantially stopped, a self-assembling material which forms a barrier to formation of adhesions. In certain embodiments, the self assembling materials are peptidomimetics, nucleotidomimetics, di- and triblock copolymers, N-alkylacrylamides, or dendimers. These materials are also useful in a method for regeneration or repair of tissue or cells forming tissue.

Self assembling peptides and peptidomimetics can be utilized for the treatment and support of disorders associated with leaky or damaged tight junction and weak, diseased, or injured extracellular matrix. The self-assembling materials generally have alternating hydrophilic or hydrophobic residues or hydrophobic and/or hydrophilic sections which allow the material to react or interact with the glycoproteins found in the ECM. Diseases in which treatment with these materials applied to or near the site in need of treatment include diabetic retinopathy, sepsis, burns, and certain neurodegenerative diseases such as Parkinson's and Alzheimer's. The formulations can be administered by injection, spraying, topically or by catheter or via a wound dressing or other material to which it is applied and then applied to the site in need of treatment.

Treatment of leaky or damaged tight junctions and enhancing extracellular matrix

A structural element comprising opposed first and second, laterally and longitudinally extended, generally planar surface structures each having a closed figure pattern of ribbing projecting therefrom toward the opposite surface structure, the ribbing being of respective heights to bridge the space between the surface structures, the opposed ribbing being interlocked in registered, mating relation.

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Manchester, MA, United States of America

Stephen Richard Kelly