University System of Maryland

Canon U.s.a., Inc.

Sonosa Medical, Inc.

Stephen Restaino

Ian M White

Jeffrey S Wolf

Marina Pranda

Rajabrata Sarkar

Aldo T Iacono

Amal Isaiah

Riddhi Gopal

The present invention relates to methods and systems for cell lysis in a microfluidic device. More specifically, embodiments of the present invention relate to methods and systems for rapid continuous flow pathogen cell lysis. In one embodiment, the microfluidic device comprises a microfluidic channel, a microporous structure within the channel, and an enzyme immobilized on the surface of the microporous structure configured to lyse pathogen cells in fluid flowing through the microfluidic channel.

Methods and systems for rapid continuous flow pathogen cell lysis in a microfluidic channel

A method and system detects a hypoxic condition during an obstruction of an airway of a subject to detect and treat obstructive sleep apnea (OSA) in the subject. The method and system includes an organ stimulating transducer configured for placement in a vicinity of an organ of the subject to stimulate the organ and remove the obstruction when OSA is detected.

System and method for diagnosis, monitoring, and treatment of obstructive sleep apnea

A method and apparatus is provided for automatic emergency airway detection. The apparatus includes a frame with a carriage guide configured to be secured around a neck of a subject. A carriage including a sensor is configured to move along the carriage guide. The sensor is configured to measure a value of a parameter indicating a topography of the neck of the subject. A processor includes a memory with instructions to receive first data from the sensor of the value of the parameter as the carriage is moved along the carriage guide and to determine, with the first data, second data indicating a position along the carriage guide corresponding to the cricothyroid region of the neck. The processor subsequently transmits a first signal indicating the second data. A method of using the apparatus is also provided.

System and method for automatic emergency airway detection

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Columbia, MD, United States of America

Stephen Restaino