New York University

Other

Luna Innovations Inc.

C Sixty Inc.

Sphere Biosystems, Inc.

Columbia University

Halliburton Energy Services, Inc.

University Patents, Inc.

Molsoft LLC

Stephen R Wilson

Randall B Murphy

Zhiguo Zhou

Quing Lu

Robert P Lenk

Douglas J Halpin

Darren K Macfarland

Kenneth L Walker

Abraham Spector

Paul A Zucker

Maxim Totrov

Yi-Zhen Hu

Norman B Javitt

Herbert H Samuels

Ruben Abagyan

Bruce M Raaka

Andreas Hirsch

Uri Sagman

Li Fan

W Orme-Johnson

A Nagahisa

Russ Lebovitz

Tong Zhu

Yi Sun

Jing Zhang

Matthieu Schapira

Christopher L Kepley

Christopher Chambers

Rajesh Shukla

Albert Bock

Christopher Kepley

A control system and method for digestion of waste activated sludge ('WAS') includes treating the WAS first at anaerobic conditions for&#x2264; a fixed period of time and then at aerobic conditions for&#x2264;a fixed period of time prior to either dewatering or optional anoxic conditions followed by dewatering, supplying air to initiate aerobic conditions when a predetermined set point for maximum ammonium nitrogen has been reached within the fixed anaerobic time, and initiating dewatering or optional anoxic conditions followed by dewatering when a predetermined set point for minimum ammonium nitrogen and optional standards for vector and pathogen reduction are met within the fixed aerobic time, the method and system including monitoring either consumption of soluble alkalinity or orthophosphate reduction or both for maximum orthophosphate reduction within aerobic time.

Systems and methods for enhanced facultative biosolids stabilization

Endohedral metallofullerene compounds, which in water has a relaxivity of about 30 mMSto about 300 mMSand forms a dispersion in water with entities having an average hydrodynamic radius of less than about 20 nm.

Metallofullerene contrast agents

A method for estimating moment tensor components of a source can use a waveform based method that performs a stack function on projected data from each sensor. The method can produce a cumulative result for each moment tensor component, for each propagation phase at each image point and origin time. A system for use in imaging a subterranean region of interest can include instructions which operate on recorded actual seismic data output from seismic receivers having known positions, and at least one processor, whereby the instructions cause the processor to project a selected data sample from the seismic data onto a moment tensor component.

System and method for moment tensor migration imaging

Described herein are methods for treating inflammatory disorders. The methods comprise administering to a subject in need thereof a therapeutically effective amount of a synthetically modified fullerene.

Fullerene therapies for inflammation

In various embodiments, methods described herein comprise the use of water-soluble cationic fullerene derivatives for improving plant genetic transformation. Cationic Fullerene derivatives of the invention possess DNA binding and compaction activity and provide a new method to deliver DNA into plant cells for plant transformation. Water-soluble fullerene derivatives of the invention with anionic or non-polar substituents possess antioxidant (free radical scavenging) activity, provide improved yields and efficiency of plant transformation methods such as biolistic,, or electroporation methods by limiting cellular damage and resulting cell death leading to higher yields of viable transformed cells in the process.

Methods for genetic plant transformation using water-soluble fullerene derivatives

A method of identification of compounds that modulate thyroid hormone activity, and the use of such compounds and compositions thereof for such purposes are disclosed. The compounds may be selected from the group consisting of: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of conditions that are causally related to aberrant thyroid hormone activity, such as hyperthyroidism and thyrotoxicosis.

Hydrazide compounds as thyroid hormone receptor modulators and uses thereof

Described herein are synthetically modified fullerene molecules, wherein the fullerene is preferably ellipsoid in shape with an equatorial band and two opposing poles, comprising an adduct at one or both poles, at least one adduct being a hydrophobic chemical moiety capable of anchoring the fullerene on or in a lipid membrane.

Amphiphilic or lipophilic polar functionalized fullerenes and their uses

High solubility of pristine single and multi-walled carbon nanotubes using electron donors as solubilizers has been observed. The resulting carbon nanotube solution can be readily diluted with other organic solvents, such as acetone, toluene and methanol. SEM after solvent evaporation clearly shows that nanotubes are still present after being subjected to this procedure. Electronic absorption of these solutions is observed in both the UV and visible region. Strong light emission (=0.30) was observed at 561 nm for dilute solutions of aniline-dissolved carbon nanotubes diluted with acetone.

Method for dissolving nanostructural materials

This patent discloses a substituted fullerenes, compositions comprising the same, and their use as antioxidants. The substituted fullerenes comprise a fullerene core (Cn) and at least one of: (i) from 1 to 6 (&#x3e;CXX) groups bonded to the fullerene core; (ii) from 1 to 18 &#x2014;Xgroups bonded to the fullerene core; (iii) from 1 to 6 &#x2014;X&#x2014; groups bonded to the fullerene core; or (iv) from 1 to 6 dendrons bonded to the fullerene core.

Substituted fullerene compositions and their use as antioxidants

Compositions and methods for administering a therapeutic agent to a mammal are disclosed. The compositions comprise either (i) vesicles comprising an amphiphilic substituted fullerene, wherein the therapeutic agent is present in the vesicle interior or between layers of the vesicle wall, (ii) a substituted fullerene, comprising a fullerene core and a functional moiety, wherein the therapeutic agent is associated with the substituted fullerene, or (iii) carbon nanotubes, wherein the therapeutic agent is covalently bonded to the carbon nanotubes.

Use of buckysome or carbon nanotube for drug delivery

The invention is directed to multiply-substituted fullerene derivatives of novel configurations, and methods for their preparation and use. The methods involve the combinatorial synthesis of a library of fullerene derivatives and comprises the steps of forming a mixture of fullerene derivatives by reacting the C fullerene with two or more reactive precursor compounds, and removing the unreacted compounds to yield the fullerene derivatives having the desired activity. Methods for the identification and screening of a combinatorial library of fullerenes by He-nuclear magnetic resonance and electrospray mass spectrometry to define members with the optimal desired activity are also provided.

Methods for the preparation and characterization of multi-substituted fullerenes

Multiply-substituted fullerenes

The invention is directed to multiply-substituted fullerene derivatives of novel configurations, and methods for their preparation and use. The methods involve the combinatorial synthesis of a library of fullerene derivatives and comprises the steps of forming a mixture of fullerene derivatives by reacting the C.sub.n fullerene with two or more reactive precursor compounds, and removing the unreacted compounds to yield the fullerene derivatives having the desired activity. Methods for the identification and screening of a combinatorial library of fullerenes by .sup.3 He-nuclear magnetic resonance and electrospray mass spectrometry to define members with the optimal desired activity are also provided.

Multi-substituted fullerenes and methods for their preparation and

Electrospray ionization mass spectroscopy (ESI-MS) methods, tagging reagents and novel compounds for labeling neutral compounds to provide ionized compounds for mass spectroscopy analysis, and novel compounds discovered using such EES-MS methods, including fulleroids

Applications of electrospray ionization mass spectrometry to neutral

Growing community of inventors

Chatham, NJ, United States of America

Stephen R Wilson