Access Business Group International LLC

Stephen R Missler

Haeri Roh-Schmidt

Jesse C Leverett

Donald J Pusateri

Amitabh Chandra

David J Fast

Arun Rajgopal

Ruo G Huang

Jeffrey A Scholten

Audra J Davies

Aaron W Crawford

Edward S Kahler

Yi Zhang

Jatinder Rana

Ernest H Brumbaugh

Kevin W Gellenbeck

Russell K Randolph

Lane A Duvel

Louise M Schneider

Yumei Lin

John F Rebhun

Kelly M Glynn

Jennifer Chuang

Valiantsina Kazlova

Penelope M Anderson

Rodney A Velliquette

Jennifer Patterson

Timothy Mulder

Marc J P Lemay

Shyam Ramakrishnan

Diego Rua

Edward W Kahler

Compositions for suppressing sebum production in skin (e.g., seborrheic skin), and minimizing glycation in skin (e.g., mature skin) with enhanced UV absorptive properties are described. In particular, the present invention relates to a composition containing a skin benefit agent that includes. Also, methods of suppressing sebum production in skin (e.g., seborrheic skin) and minimizing glycation in skin (e.g., mature skin) by applying a composition to the skin, wherein the composition comprises an effective amount of a derivative ofare also described.

Topical compositions of(gromwell root) for treating or controlling excessive oil production in skin and minimizing glycation in skin, and methods of using the compositions

A supplement including a blend of turmeric, quercetin and rosemary, or holy basil, wasabi, and broccoli seed extract which are present in a balanced and predetermined ratio, and which stimulate the Antioxidant Response Element (ARE), Quinone Reductase, and/or induce related gene expression, for example, heme oxygenase-1 (HMOX-1) expression. The blend of ingredients can be formed as or in a dietary supplement adapted for administration to a subject. The dietary supplement can be formulated so that the turmeric, quercetin and rosemary are present in a predetermined ratio of 1:3:5, or holy basil, wasabi, and broccoli seed extract in a predetermined ratio of 1:1:0.2. Additional ingredients can be included in the supplement. The supplement can synergistically affect natural antioxidant response pathways within cells of a subject to whom the supplement is administered. A related method of use is also provided.

Antioxidant dietary supplement and related method

Topical compositions, packaging systems and methods for improving the appearance of skin or at least one sign of aging in skin including Kachnar are described.

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A composition including a unique combination of fruits, vegetables, herbs, and optionally vitamins, minerals and specialty ingredients. The composition can include a fruit ingredient, a vegetable ingredient and an herbal ingredient, wherein the fruit ingredient is at least one of pomegranate and citrus bioflavonoids, wherein the vegetable ingredient, is at least one of asparagus, lutein, lycopene and watercress, and wherein the herbal ingredient is at least one of basil, oregano and rosemary. The composition can be administered to subjects to correct a dietary deficiency of phytochemicals and other nutrients, improve plasma concentrations of antioxidant nutrients, and increase the activity of genetic mechanisms for DNA repair and stability.

Dietary supplement and related method

The present invention relates to methods of increasing tyrosinase synthesis, expression, or activity in a cell comprising administering at least one grape seed extract to the cell. The grape seed extract may be obtained by any extraction process including solvent sequential fractionation and supercritical fluid extraction.

Methods of using grape seed extract to stimulate tyrosinase gene expression

Disclosed herein is a composition comprising a liposome, a cardiolipin, and at least one antioxidant, wherein the composition is useful for improving, maintaining, or restoring a mitochondrial membrane and/or mitochondrial function. In one example, the liposome is primarily composed of phosphatidylcholine, the cardiolipin is tetraoleoyl-cardiolipin, and the at least one antioxidant is methylgentisate, l-carnosine, or both. The composition may be topically administered, orally administered, or parenterally administered, for example administered by injection. If topically administered, the composition may be administered for example, as a cream, lotion, gel, paste, spray, tonic, or other suitable form and may contain various additives, for example, one or more of an emollient, a humectant, a penetration enhancer, a vitamin, a fragrance, a pigment, and a moisturizer.

Liposome containing cardiolipin for improvement of mitochondrial function

A dietary supplement including a unique combination of fruits, vegetables, herbs, and optionally vitamins, minerals and specialty ingredients. The supplement can include a fruit ingredient, a vegetable ingredient and an herbal ingredient, wherein the fruit ingredient is at least one of pomegranate and citrus bioflavonoids, wherein the vegetable ingredient is at least one of asparagus, lutein, lycopene and watercress, and wherein the herbal ingredient is at least one of basil, oregano and rosemary. The supplement can be administered to subjects to reduce risk factors in a subject, for example, by lowering homocysteine levels and/or reducing DNA damage. The supplement can increase plasma levels of at least one of vitamin B6, Vitamin B12, folate, and beta-carotene and other vitamins or substances in the subject.

A dietary supplement including a unique combination of fruits, vegetables, herbs, and optionally vitamins, minerals and specialty ingredients. The supplement can include a fruit ingredient, a vegetable ingredient and an herbal ingredient, wherein the fruit ingredient is at least one of pomegranate and citrus bioflavonoids, wherein the vegetable ingredient is at least one of asparagus, lutein, lycopene and watercress, and wherein the herbal ingredient is at least one of basil, oregano and rosemary. The supplement can be administered to subjects to correct a dietary deficiency of phytochemicals and other nutrients, improve the amount of antioxidants in the subject, and decrease free radical damage in the subject.

A skin whitening composition includes an extract of black cohosh obtained by sequentially exposing the black cohosh to two or more solvents of varying solvent strengths. The root of the black cohosh can be separately used to obtain the extract. The composition can be topically applied to the human skin and can further include one or more cosmetically acceptable ingredients. A method of suppressing melanogenesis includes topically applying to the skin a composition comprising an extract of black cohosh obtained by sequentially exposing the black cohosh to two or more solvents of varying solvent strength.

Skin whitening compositions containing black cohosh extract

A skin whitening composition includes an extract of asparagus obtained by sequentially exposing the asparagus to two or more solvents of varying solvent strengths. The root and shoot portions of the asparagus can be separately used to obtain the extract. The composition can be topically applied to the human skin and can further include one or more cosmetically acceptable ingredients. A method of suppressing melanogenesis includes topically applying to the skin a composition comprising an extract of asparagus obtained by sequentially exposing the asparagus to two or more solvents of varying solvent strengths.

Skin whitening compositions containing asparagus extract

A skin whitening composition includes an extract of black cohosh obtained by sequentially exposing the black cohosh to two or more solvents of varying solvent strengths. The root of the black cohosh can be separately used to obtain the extract. The composition can be topically applied to the human skin and can further include one or more cosmetically acceptable ingredients. A method of suppressing melanogenesis includes topically applying to the skin a composition comprising an extract of black cohosh obtained by sequentially exposing the black cohosh to two or more solvents of varying solvent strengths.

Growing community of inventors

Grand Rapids, MI, United States of America

Stephen R Missler