Cdrd Ventures Inc.

Simon Fraser University

Acuitas Therapeutics, Inc.

Stephen Paul Arns

Tom Han Hsiao Hsieh

Richard Tom Liggins

James Brian Jaquith

Eric Roy Simonson

Nag Sharwan Kumar

Robert N Young

Steven Michial Ansell

Xinyao Du

Mohammed Monzur Morshed

Julia Gatenyo

Davy Jérémy Baudelet

Anne Moreau

Romelo Gibe

Jason Samuel Tan

Polina Blagojevic

SOMATOSTATIN RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USING THE SAME

Compounds are provided having the following structure: or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R, L, L, G, Gand Gare as defined herein. Use of the compounds as a component of lipid nanoparticle formulations for delivery of a therapeutic agent, compositions comprising the compounds and methods for their use and preparation are also provided.

Lipids for use in lipid nanoparticle formulations

The present invention is directed to somatostatin receptor antagonist compounds having the structure of Formula I, compositions comprising the same, and methods of using such compounds and compositions. The compounds may be useful in the prevention or treatment of hypoglycemia. 

Somatostatin receptor antagonist compounds and methods of using the same

The invention provides in part, conjugate compounds. The invention also provides synthesis methods for making the compounds, and uses of the compounds.

Prostaglandin-bisphosphonate conjugate compounds, methods of making same, and uses thereof

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Vancouver, Canada

Stephen Paul Arns