Eli Lilly and Company

Stephen M Spaethe

George J Cullinan

Donald G Carlson

Kennan Joseph Fahey

William T Jackson

Neal W Roehm

Jason Scott Sawyer

James J Starling

This invention provides a method of reversing multidrug resistance in a multidrug resistance tumor comprising administering a multidrug resistance reversing amount of any of a series of phenoxy compounds as defined herein.

Method for treating resistant tumors

Provided are compounds of the formula II ##STR1## wherein R.sub.6 and R.sub.7 are independently hydrogen or C.sub.1 -C.sub.6 alkyl;

Benzothiophenes substituted at the 3-carbonyl

A method of inhibiting 5-lipoxygenase comprising administering to a mammal in need thereof an effective amount of a compound having the formula ##STR1## wherein R.sub.1 and R.sub.2 are independently hydrogen or C.sub.1 -C.sub.6 alkyl;

Benzothiophene compounds useful for inhibiting lipoxygenase

A method of inhibiting leukotrienes comprising administering to a mammal in need thereof an effective amount of a compound having the formula ##STR1## wherein R.sub.1 and R.sub.2 are independently hydrogen or C.sub.1 -C.sub.6 alkyl;

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Carmel, IN, United States of America

Stephen M Spaethe