Anika Therapeutics, Inc.

Stephen J Kennedy

Charles H Sherwood

Tamera B Gooding

Steven W Ek

Edward S Ahn

Sonali Puri

Matthew M Mannarino

Robert Richard

Elvira Marchetto

Stefano Agnello

Sara Simoncioni

Morgan Davis Kennedy

Matteo Centola

A bioabsorbable textile for the restoration of the joint function whereas the joint is affected by partial thickness tears, small to medium full-thickness tears, large to massive full-thickness tears, acute and chronic/degenerative tears. The bioabsorbable textile may comprise polymeric yarns interconnected to form a weave or knitted configuration, wherein said bioabsorbable textile provides a combined mechanical and biological augmentation in the target joint tissue. The bioabsorbable textile may be implanted in combination with fixation tools during open, mini-open or arthroscopic repair/augmentation procedures of joint tissue tears.

Bioabsorbable textiles and methods for joint function restoration

A digitally controlled mobile ground launching fire retardant delivery system. The system is configured to launch fire retardant projectiles at wildfires located in a small fire area that is considered inaccessible by fire personnel, due to the terrain, elevation and/or remote location. The system is also advantageously configured to launch soft-ball size objects at remote wildfires. The soft ball sized objects will contain at least one beneficial fire-retardant substance contained therein.

Digitally controlled mobile ground launching fire retardant delivery system

A method of treating a subject having a musculoskeletal disorder includes administering to a subject's articular site in need thereof an effective amount of a hyaluronic acid (HA) composition. In one embodiment, the HA composition includes an HA derivative, wherein carboxyl functionalities of the hyaluronic acid derivative are each independently derivatized to include an N-acylurea or O-acyl isourea, or both N-acylurea and O-acyl isourea. In another embodiment, the HA composition includes a crosslinked HA gel that is prepared by reacting an uncrosslinked HA with a biscarbodiimide in the presence of pH buffer in a range of between about 4 and about 8. The composite can optionally include at least one second bioactive agent other than the HA derivative, such as a steroid.

Treatment of arthritis and other musculoskeletal disorders with crosslinked hyaluronic acid

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Hudson, NH, United States of America

Stephen J Kennedy