Mallinckrodt, Inc.

Covidien LP

Stephen H Wu

Jun Yang

Cliff J Herman

William H Nau, Jr

Francesca Rossetto

Rachit Ohri

Phillip Blaskovich

Les Hull

Lan Pham

Allison Waller

Rupal Ayer

Wenxing Huang

Paul DiCarlo

Harold M Martins

Jiagui Li

Qinlin Gu

Mantao Xu

Xingyan Lu

Paul Dicarlo

Phillip D Blaskovich

The present invention provides methods for delivery of therapeutic agents to a subject using multi-component liposomal systems. The methods include administration of a therapeutic liposome containing an active agent, followed by a administration of an attacking liposome that induces release of the agents from the therapeutic liposome.

Combinational liposome compositions for cancer therapy

A drug-delivery cannula assembly includes a cannula housing adapted for receiving at least one obturator shaft of an obturator assembly therethrough, one or more cannulae, and a supply line coupled to the cannula housing. The cannula housing is adapted for receiving one or more obturator shafts of an obturator assembly therethrough. The one or more cannulae define a longitudinal axis and a passageway aligned with the longitudinal axis. The one or more cannulae each include a proximal end coupled to the cannula housing. The cannula housing is configured to fluidly-couple the one or more cannulae to a source of a drug delivery supply for supplying drugs via the supply line to the one or more cannulae.

Drug-delivery cannula assembly

A drug-delivery device includes a body configured for attachment to a handle of an ablation device, a shaft portion defining a passageway therein, and a delivery lumen to provide for drug delivery to tissue. The body includes a proximal portion, a distal portion, and a contoured portion disposed therebetween. The contoured portion is configured for engagement with a contoured portion of the handle of the ablation device. The shaft portion includes a proximal end and a distal end. The proximal end of the shaft engages with an opening defined in the distal end of the body. The passageway of the shaft portion is configured to receive the delivery lumen slideably moveably therein. The delivery lumen includes a proximal portion and a distal portion. The drug-delivery device also includes a knob member coupled to the proximal portion of the delivery lumen.

Drug-delivery device for use with ablation device

Growing community of inventors

Chesterfield, MO, United States of America

Stephen H Wu