Eastman-kodak Company

Eastman Chemical Company

Rhone-poulenc Nutrition Animale

Stephen H Wu

Carol J Greene

Kimberly T Peters

Mahendra K Sharma

Shane Kipley Kirk

Clarence C Dannelly

M Akram Sandhu

E Phillip Smith

Warren Kent Hopkins

Edward G Miller, Jr

Waylon Lewellyn Jenkins

Stephen Weinhold

Charles A McCombs

Chung-Ming Kuo

Mohammad A Sandhu

Pierre Autant

Yeong-Ho Chang

Andreas M Papas

Ernest Phillip Smith

David S Kashdan

Robert G Chen

Jacques Ruel

Michael Wayne Adams

Louis P Hoskins

Charles H Benton

Kenneth P Perry

Disclosed herein is an aqueous enteric coating composition comprised of a solution of a water-soluble salt of an enteric coating polymer, with a hydrophobic compound containing 12 to 20 carbon atoms and a water-insoluble solid flake material dispersed in the aqueous solution. The enteric coating formed from the present composition has good mechanical strength and shows superior resistance to attack by atmospheric moisture and simulated gastric fluid, while being readily broken down under the alkaline conditions which exist in the intestine.

Aqueous enteric coating composition and low gastric permeability enteric

The present invention sets forth an enteric coating composition comprising a blend of

Aqueous enteric coating compositions

This invention is based on the discovery that certain cellulose acetoacetate mixed esters will remain insoluble in mild (near-neutral) or acidic aqueous solutions, but dissolve under alkaline conditions. The esters are particularly useful as coatings for controlled-release applications. Coatings comprising these esters will dissolve to release a coated active agent under alkaline conditions, the exact pH at which dissolution occurs being adjustable.

PH-sensitive coatings based on cellulose acetoacetate

The present invention relates to a hemostatic composition comprising 1 to 90 weight percent of vitamin E or a derivative of vitamin E, 1 to 95 weight percent of oxidized cellulose, and 0.1 to 75 weight percent of water. The hemostatic composition may be formed into pellets, powder, paste, gum, gel, or liquid suitable for molding to conform to the contours of a wound.

Oxidized cellulose and vitamin E blend for topical hemostatic

Water dispersible polyester polymers, polyesteramides polymers and blends of these polymers are dispersed in water and spray dried to form fine powders. In the solid state, these powders can absorb oils and/or diffuse ambient light, thereby resulting in the production of significant reduction in gloss and tack of lipids in cosmetic and personal care products when applied to ordinarily oily skin.

Oil absorbing polymers

Provided is a process useful for preparing acrylic polymers of methacrylic acid and ethyl acrylate. The process provides polymers useful as enteric coatings for medicaments in solid form, said coatings having improved effectiveness, reproducibility and coating efficiency. Also provided are medicaments in solid form coated with such polymers.

Process for the preparation of acrylic polymers for pharmaceutical

Provided is a controlled-release system for delivery of bioactive materials such as medicaments, cosmetic ingredients and agrichemicals using cellulose acetate succinate or certain blends of cellulose acetate phthalate polymers as enteric coating materials. Also provided is a method for delivering active ingredients to animals utilizing the controlled-release system of the invention.

Controlled-release delivery system

The present invention relates to new granules, as well as the process for their preparation, obtained by extrusion of a mixture containing a meltable binder in an amount such that it permits the passage of the mixture through a die. The granules obtained are then coated with a polymer permitting their trans-rumen passage without degradation. After coating, these granules are used for animal feeding of ruminants.

Extrusion of an admixture of a meltable binder and a food or drug

The present invention concerns a process for preparing a treated blend which contains pigment material dispersed in a continuous phase of water and a polyester material. The invention also concerns compositions prepared from such process. The polyester material of the treated blend is linear, contains a sulfomonomer, and has an average particle size of less than 1 .mu.m.

Process for treating pigments

A composition for increased bioavailability of Vitamin E. The composition contains a Vitamin E material, a surface active agent, an inert carrier, and, optionally, a flow agent.

Nutritional supplement containing Vitamin E

Taste-masking composition for oral delivery of medicaments to non-ruminants, especially humans. The taste-masking composition contains a polymeric composition containing a flake material, a hydrophobic material, and a polymer containing repeating units from vinylpyridine derivatives. Also disclosed is a process for purifying polymers.

Method for purifying high molecular weight vinylpyridine/styrene

Disclosed is a process for preparing polymeric compositions which are suitable for coating medicaments or for use in cosmetic formulations and the novel compositions prepared therefrom. The process makes stable, colloidal, latex-like dispersions of coating polymers which can be readily dried to form polymeric powder materials. The process makes use of a novel combination of a water-in-oil emulsifier and an oil-in-water emulsifier.

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Kingsport, TN, United States of America

Stephen H Wu