Other

Abbott Laboratories Corporation

Stephen H Dailey

Suresh M Desai

Sushil G Devare

George J Dawson

James M Casey

Robin A Gutierrez

James L Stewart

Richard R Lesniewski

Kevin R Rupprecht

Smriti U Mehta

Jill E Johnson

A self-disinfecting medication vial cap assembly for a medication vial includes a needle-penetrable assembly base configured for attachment to the medication vial; an assembly cap carried by the assembly base, the assembly base and the assembly cap having a cap interior and the assembly cap positional between closed and open positions; a rupturable antiseptic pouch attached to the assembly base and the assembly cap in the cap interior; and an antiseptic contained in the antiseptic pouch. The antiseptic pouch remains intact in the closed position of the assembly cap. The antiseptic pouch ruptures and the antiseptic is discharged onto the assembly base upon movement of the assembly cap from the closed position to the open position.

Self-disinfecting medication vial cap assembly

Unique recombinant antigens representing distinct antigenic regions of the Hepatitis C Virus (HCV) genome which can be used as reagents for the detection of antibodies and antigen in body fluids from individuals exposed to HCV. The present invention also provides an assay for detecting the presence of an antibody to an HCV antigen in a sample by contacting the sample with the recombinant antigens. Preferred assay formats include a screening assay, a confirmatory assay, a competition or neutralization assay and an immunodot assay.

Hepatitis C assay utilizing recombinant antigens

The present invention provides unique recombinant antigens representing distinct antigenic regions of the Hepatitis C Virus (HCV) genome which can be used as reagents for the detection of antibodies and antigen in body fluids from individuals exposed to HCV. The present invention also provides an assay for detecting the presence of an antibody to an HCV antigen in a sample by contacting the sample with the recombinant antigens. Preferred assay formats include a screening assay, a confirmatory assay, a competition or neutralization assay and an immunodot assay.

Monoclonal antibodies which specifically bind to Hepatitis C Virus (HCV) E2/NS1 antigen. Also provided are hybridoma cell lines which secrete these monoclonal antibodies, methods for using these monoclonal antibodies, and assay kits for assays which contain these monoclonal antibodies.

Monoclonal antibodies to putative HCV E2/NS1 proteins and methods for

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Vernon Hills, IL, United States of America

Stephen H Dailey