Sanofi-A Ventis Deutschland Gmbh

Sanofi

Stephen Francis Gilmore

Paul Richard Draper

Anthony Paul Morris

James Robert Coop

James Anthony West

Joseph Butler

Stefan Blancke

Mark Digby Teucher

Daniel David Higgins

Ralph Donald Quentin Collings

David Aubrey Plumptre

Naceur Rekaya

Paul Roger Griffin

Matthew Meredith Jones

Michael Jugl

Samuel Steel

David Moore

Axel Teucher

William Geoffrey Arthur Marsh

Sophie Louise Sladen

David Richard Mercer

Barry Yates

George Cave

Paul Graham Hayton

Jack Carroll

Timothy Robin Quigg

Laura Stein

Denny Lustosa Horn

A drive train for a wind-up injection device, comprises a torsional energy storage adapted to be loaded or unloaded by a rotatable element, a rotatable user handle coupled with a button, a rotationally drivable expelling mechanism, and a clutch element coupled with the torsional energy storage via the rotatable element and comprising a ratchet for maintaining the rotatable element at one of a number of discrete angular positions, wherein via the rotatable element, the clutch element is adapted to transmit a torque from the user handle to the torsional energy storage or from the torsional energy storage to the expelling mechanism, and wherein the ratchet is switchable from one position to an adjacent position by a torque transmitted from the user handle to the torsional energy storage, and wherein the drive train is adapted to dampen torque peaks by a flexible impact portion in the area of the clutch element.

Drive train for dial of a torsion-spring assisted wind-up injection device

An assembly for a drug delivery device is provided, the assembly comprising a feedback feature. The feedback feature is configured to indicate an end of the dispense operation to a user by giving an audible and/or tactile feedback.

Assembly for a drug delivery device comprising a feedback feature

A button for a drug delivery device with a reduced operating loudness includes a plate-like button body forming a touch surface, wherein the plate-like button body is coupled by an axial supporting member to a noise-generating interface of the drug delivery device and movable into a longitudinal direction of the drug delivery device, wherein the plate-like button body includes a material composite with at least one first component consisting of a first material and at least one second component consisting of a second material different from the first material, wherein the at least one first component and the at least one second component are coupled via at least one coupling plane that is at least sectionwise slanted or perpendicular to the longitudinal direction. Further, the disclosure describes a button assembly for a drug delivery device which is shock resistant.

Button and button assembly for a drug delivery device

A drive train for a wind-up injection device is described. The drive train includes a torsional energy storage adapted to be loaded or unloaded by a rotatable element, a rotatable user handle, a rotationally driveable expelling mechanism adapted to expel the liquid drug, and a clutch element coupled with the torsional energy storage via the rotatable element and including a ratchet for maintaining the rotatable element at one of a number of discrete angular positions against the torque of the torsional energy storage. The clutch element is adapted to transmit the torque from the user handle to the torsional energy storage, or alternatively from the torsional energy storage to the expelling mechanism. The ratchet is switchable from one position to an adjacent position by a torque transmitted from the user handle to the torsional energy storage. The drive train is adapted to dampen torque peaks visco-elastically and/or visco-frictionally.

The invention relates to an arrangement for detecting a position of a plunger () relative to a bung () in a drug cartridge (), comprising a proximity sensor () located close to a distal end () of the plunger () facing the bung () and aligned to receive light reflected by the bung ().

Arrangement for detecting a position of a plunger

A drive mechanism for a drug delivery device with a reduced operating loudness includes a dose selector, a housing, and a ratchet with a gear element comprising a plurality of gear teeth connected with the dose selector and a pawl element rotationally constrained to the housing comprising at least one pawl tooth. The at least one pawl tooth engages with the gear teeth and is located opposite to the gear teeth. One of the gear element and the pawl element moves forth and back relative to the other element of the gear and pawl elements along a first direction for de-engagement and re-engagement of the opposite gear teeth and at least one pawl tooth when the gear element rotates relative to the housing during dose setting using the dose selector. The pawl element and/or gear element comprises a noise reduction characteristic at a surface which dampens the noise produced.

Drive mechanism with noise reduction

A system comprises a first member, a second member, and a third member, wherein the first and second members are rotatable relative to the third member, wherein the first and second members are coupled to one another by a dead-angle follower coupling, wherein the dead-angle follower coupling is configured such that the first and second members are rotatable relative to one another, wherein the second and third members are rotationally coupled to one another by a switchable coupling mechanism, wherein the switchable coupling mechanism is switchable between two different states, a locked state and a non-locked state, wherein the maximum torque transferable between the second and third members via the switchable coupling mechanism in the locked state is greater than in the non-locked state, wherein the switchable coupling mechanism is in the locked state when the first member is in a locking position relative to the second member.

Ratchet systems for drug delivery devices

A drive mechanism of a drug delivery device and a respective drug delivery device for setting and dispensing of a dose of a medicament are presented, where the drive mechanism has an elongated housing extending in an axial direction, a piston rod to operably engage with a piston of a cartridge containing the medicament, a dosing arrangement manually and axially displaceable relative to the housing for setting and dispensing of the dose, and an accessory drive operably engaged with the piston rod to support a manually operated dose dispensing displacement of the dosing arrangement.

Drive mechanism of a drug delivery device comprising an accessory drive

Drug delivery device comprising a housing retaining a primary drug delivery assembly for the delivery of a primary medicament with a primary dose setting member configured to rotate in a helical movement to set a dose of the primary medicament and a secondary drug delivery assembly for the delivery of a secondary medicament. A dose dial is movable between a first position and a second position in axial direction and is rotationally constrained with respect to the housing when moved from the first position into the second position and is rotationally constrained to the primary dose setting member in the second position for setting a dose of the primary medicament. A secondary drive sleeve of the secondary drug delivery assembly serves for dispense of the secondary medicament. The dose dial and the secondary drive sleeve can be coupled for dose setting.

Drug delivery device

An assembly for a drug delivery device is provided, the assembly comprising an actuator which is configured to be operated in order to dispense a dose of medication and a feedback feature being configured to give a feedback signal to a user at the end of a dwell period after the actuator has reached an end position.

A drug delivery device comprising: a housing; a plurality of sensors; and a cylindrical member supported within the housing, an outer surface of said cylindrical member being provided with a helical track, the helical track comprising track segments of a first type and track segments of a second type, the first and second types of track segments being respectively capable of inducing first and second responses in the sensors; wherein: the helical track has a width; the helical track includes across the width of the helical track at least one track segment of the first type and at least one track segment of the second type at plural positions along a length of the helical track; the device is configured such that during a first phase of a drug delivery operation the helical track is moved axially, without rotation, relative to the plurality of sensors between a first position and a second position, and during a second phase of the drug delivery operation the track is moved helically relative to the plurality of sensors from the second position; and responses induced in the plurality of sensors by the track segments of the helical track are different in the first position compared to responses induced in the plurality of sensors by the helical track in the second position.

Growing community of inventors

Bristol, United Kingdom

Stephen Francis Gilmore