Mermaid Care A/s

Covidien LP

Other

Roche Diagnostics Gmbh

Aalborg Universitet

Obi Aps

Obi Aps, C/o Per Thorgaard

Stephen Edward Rees

Dan Stieper Karbing

Steen Andreassen

Bruno Graversen

Claus Lindholt

Egon Steen Toft

Lars Pilegaard Thomsen

Lisha Shastri

Sebastian Larraza Rico

Per Thorgaard

Soren Christensen Kjaergaard

Jakob Bredal Jensen

The present invention relates to a method for identification of tissue hypoxia from measurements of acid-base and oxygenation status from venous and/or arterial blood.

Identification and quantification of the degree of tissue hypoxia

A ventilator system is capable of displaying complex information patterns in a GUI, thereby allowing a clinician to get subtract complex information from multiple parameters inputs.

Decision support system for lung ventilator settings

The present invention relates to a system () and a corresponding method for estimating the respiratory drive (R_DRIVE) of mechanically ventilated patients, and for preferably apportioning this respiratory drive into one, or more, components related to the chemical drive&#x2014;i.e. the drive due to the chemoreceptor response&#x2014;and/or the muscular drive&#x2014;i.e. the contraction of respiratory muscles, for example the diaphragm. The principle of the invention is that respiratory drive can be obtained from measuring the patient's response to small changes in mechanical ventilation settings (Vt_SET), and that this can be apportioned into chemical and/or muscular effects depending upon the changes in respiratory frequency, and/or arterial or end tidal COlevels, and/or arterial blood p H.

System and a corresponding method for estimating respiratory drive of mechanically ventilated patients

The present invention relates to a decision support system (DSS), a medical monitoring system (), and a corresponding method for identifying the need for measurement of cardiac output (CO) based on one or more comparisons (COMP, COMP) in a physiological model. More specifically, for identifying when an approximated value of CO cannot be correct due to circulatory compromise and as such that another estimated or measured value of CO is required.

Systems and method for identifying the need for measurement of cardiac output

The invention relates to a device for determining two or more respiratory parameters relating to an individual and a method for determining two or more respiratory parameters relating to an individual by means of the device. The disclosed device and method may be used in an individual suffering from pulmonary gas exchange problems relating to gas exchange of oxygen and/or carbon dioxide, e.g. a patient with chronic obstructive pulmonary disease. The device and method may also be used in a healthy individual or in an animal, e.g. for research experiments. The device has detection means for oxygen and carbon dioxide contents in inspired and expired gas and blood. The device is controlled by a computer with functionality for entering oxygenation, carbon dioxide and acid-base values from one or more blood samples from arterial, venous, central venous or mixed venous blood samples, and with the parameter estimation based on equations of gas exchange of both oxygen and carbon dioxide and equations describing the acid-base chemistry of blood potentially including the competitive binding of oxygen and carbon dioxide to hemoglobin.

Automatic lung parameter estimator for measuring oxygen and carbon dioxide gas exchange

A methodology for converting venous blood values to arterial blood values provides the advantage of obviating the need for taking arterial blood samples. The method entails (i) measuring arterial oxygenation, (ii) measuring and estimating values of venous blood acid/base status and oxygenation status of a venous blood sample, and (iii) converting the venous blood values by applying a mathematical model for deriving blood acid/base status and oxygenation status into estimated arterial blood values.

Method, system and devices for converting venous blood values to arterial blood values

A device for determining one or more respiratory parameters relating to an individual is disclosed, as well as a method for determining one or more respiratory parameters by means of the device, wherein the individual is suffering from hypoxemia or is at risk of hypoxemia. However, the method and the device may also be applied to healthy individual e.g. for testing of medicaments. The device is controlled by a computer equipped with suitable software and includes functionality for on-line continuous data collection, automatic assessment of the timing of measurements, automatic assessment of the next target (oxygen saturation of arterial blood (SpO2)), automatic assessment of the appropriate fraction of oxygen in inspired gas (FIO2) settings to achieve the target SpO2, automatic control of the FIO2, on-line parameter estimation, and automatic assessment of the number of measurememts requied.

Growing community of inventors

Gistrup, Denmark

Stephen Edward Rees