Nostix LLC

Other

Datex-ohmeda, Inc.

Ohmeda Inc.

Vixel Corporation

Square One Technology, Inc.

Stephen D Walker

Peter E Nelson

R Dale Zellers

Charles W Henry

John E Repine

Russell John Fischer

Patrick Francis Crane

Clement Lim Yu

James Roswell Braig

Jack L Jewell

Daniel S Goldberger

Stanley E Swirhun

Harry L Valenta, Jr

Greg R Olbright

Robert A Nichols

Sophat Svai

William A Curnan

Glucose concentration is noninvasively measured by measuring a plurality of absorption values using at least one emitter operating at a corresponding plurality of emission wavelengths through a common optical sample volume and deriving glucose concentration from the absorption measurement values.

Noninvasive glucose sensor

An optical sensor includes an optical source capable of being positioned on a tissue and emitting near infrared light into the tissue at a plurality of selected wavelengths, and a photodetector capable of detecting reflected light from the tissue. The photodetector being positioned on the tissue removed from the optical source but sufficiently close in proximity to the optical source to contact the same general tissue. The optical sensor further includes an oscillator coupled to the optical source and capable of activating the optical source to emit the near infrared light, and a modulator coupled to the oscillator and capable of controlling radio frequency modulation of the optical source to emit a radio frequency component that is used to measure the optical path length and absorbance of an analyte of interest within the tissue.

Noninvasive optical sensor for measuring near infrared light absorbing analytes

A diagnostic apparatus includes a near infrared spectrophotometer (NIRS) and an ultrasound transducer that operate in combination to improve diagnostic measurements. The diagnostic apparatus includes a near infrared spectrophotometer that measures an analyte, for example tissue oxygenation, in an optical sample volume and an ultrasound imager to accurately position the optical sample volume in biological tissue or vessels. In one example, the diagnostic apparatus includes an optical source, a linear array of ultrasound transducers, and an optical photodetector arranged in the same plane so that the ultrasound sample volume interrogated by the ultrasound transducers intersects the optical sample volume formed by the optical source and detector.

Ultrasound-guided near infrared spectrophotometer

A method and apparatus for determining oxygenation and hemoglobin parameters in tissue measures light scattering parameters of light directed through the tissue, using an array of VCSELs, for light directed at more than one frequency. This allows for the calculation of Hb, HbO , and other parameters.

Cerebral oxygenation monitor

A system and method for determining the concentration of an analyte such as oxygen in an unknown gas sample. A Vertical Cavity Surface Emitting Laser (VCSEL) is used as a variable wavelength light source which is 'swept' through a wavelength range by varying the drive signal applied thereto. Quantitative spectroscopic analysis of the unknown gas sample is performed without the requirement of feedback circuitry for tuning the light source to the characteristic frequency of an analyte. Instead, the VCSEL is repeatedly 'swept' through a range of frequencies determined by the drive signal, and the absorption is measured by the detector. The absorption lines do not always occur at the same place but instead move along around during the sweep based on the temperature and baseline current. The absorption at a particular wavelength may be determined by overlaying the drive signal and its timing information over the detected absorption signal.

Method and apparatus for measuring gas concentration using a

The gas sample identification apparatus transmits at least one beam of light of predefined frequency band through a gas sample present in a gas sampling chamber. The presence and concentration of various agents in the gas sample are determined by a linear variable filter that selectively passes the light beam transmitted through the gas sample chamber to an array of detectors. The detectors are positioned to receive only a narrow passband component of the light beam. The output signals from the array of detectors is processed by a multivariate statistical processor to accurately identify both the presence and concentration of one or more agents contained in the gas sample.

Apparatus for automatic identification of gas samples

An on-airway breath-by-breath oxygen sensor is described which has the necessary low weight, fast response and high precision required for oxygen consumption measurement. A vertical-cavity surface-emitting laser (VCSEL) is continuously tuned to emit light at the resonance of oxygen, or more generally, the molecular species of interest. The light beam is directed through a sample containing the molecular species of interest onto a detector. The amount of light absorbed is approximately proportional to the concentration of the molecular species of interest in the sample.

Sensor for analyzing molecular species

Growing community of inventors

Boulder, CO, United States of America

Stephen D Walker