Abbott Cardiovascular Systems, Inc.

Advanced Cardiovascular Systems, Inc.

Abbott Laboratories Corporation

Other

Depuy Spine, Inc.

Orquest, Inc.

Depuy Acromed, Inc.

Advanced Cardiovascular, Inc.

Abbott Cardiovascular

Stephen D Pacetti

Syed F A Hossainy

Thierry Glauser

Ni Ding

Lothar W Kleiner

Syed Faiyaz Ahmed Hossainy

Yiwen Tang

Jessica R DesNoyer

Wouter Erik Roorda

Eugene T Michal

John Joseph Stankus

Paul M Consigny

Florian Ludwig

Yunbing Wang

Judy A Guruwaiya

Deborra Sanders Millare

Mikael Trollsas

Daryush Mirzaee

Dariush Davalian

Evgenia Mandrusov

Vinayak Bhat

Keith Edward Fong

David C Gale

Yung-Ming Chen

Victoria May Gong

Syed F Hossainy

Daniel A Castro

Irina Astafieva

Connie S Kwok

Plaridel Kimpo Villareal

James Oberhauser

Fuh-Wei Tang

Anthony S Andreacchi

Charles David Claude

Ronald Kenichi Yamamoto

Anthony J Abbate

Diem Uyen Ta

Manish Gada

Binh T Nguyen

Bin Huang

John E Papp

Michael H Ngo

Jason Van Sciver

Julia Fox

Xiao Ma

Joel Harrington

O Mikael Trollsas

Gina Zhang

Timothy A Limon

Chad Joseph Abunassar

Murthy V Simhambhatla

Klaus Kleine

Jinping Wan

Emmanuel C Biagtan

Douglas H Gesswein

Stephen R Dugan

Svava Maria Atladottir

Hung T Nguyen

Ashok A Shah

Richard Rapoza

Katsuyuki Murase

Bozena Zofia Maslanka

Michael J Leonard

Florian Niklas Ludwig

John Arthur Simpson

Daniel L Cox

Darrin James Kent

David K Wrolstad

Florencia Lim

Rommel Lumauig

Fozan El-Nounou

Pamela A Kramer-Brown

Gordon S Stewart

Jill A McCoy

Senthil Kumar Eswaran

Erik David Eli

Ty T Hu

Leonard Darius Barbod

Jessie Delgado

Kurt W Scheinpflug

Ronald W Heil, Jr

Michael L Green

Aaron M Fortson

Santosh V Prabhu

Sean A McNiven

Keith R Cromack

Benjamyn Serna

Matthew J Gillick

James K Hong

John L Toner

Steven Z Wu

Jeffrey B Huff

Bryan K Clark

Jeffrey T Ellis

Gene Michal

Thomas David Esbeck

Dudley Shelton Jayasinghe

Mark C Johnson

Sameer Harish

Brenna Hearn Lord

An access closure device for closing an opening in tissue is provided. The access closure device may comprise a balloon delivery system and a sealant delivery system. The balloon delivery system may comprise a suture, a delivery shaft, an inflatable balloon, and a balloon segment releasably attached to the delivery shaft. The sealant delivery system may comprise a sealant delivery shaft, an ejection tube, and a snare wire configured to snare a suture of the delivery system.

Access closure device

A medical device includes a balloon expanded scaffold crimped to a balloon catheter. The scaffold has a network of rings formed by struts connected at crowns and links connecting adjacent rings. The scaffold has a polymer coating and is crimped to the balloon. The scaffold is rotated, or allowed to rotate during crimping to improve results from crimping, such as reduced damage to the coating.

Rotation of a medical device during crimping

An apparatus and method for controlling inflation pressure, pressurization rate, and volumetric flow rate of a balloon during deployment of a stent or scaffold is disclosed.

Flow regulation valve for controlling inflation rate of a balloon deploying a scaffold

Embodiments are directed to radiopaque implantable structures (e.g., stents) formed of cobalt-based alloys that comprise cobalt, chromium and one or more platinum group metals, refractory metals, precious metals, or combinations thereof. Platinum group metals include platinum, palladium, ruthenium, rhodium, osmium, and iridium. Refractory metals include zirconium, niobium, rhodium, molybdenum, hafnium, tantalum, tungsten, rhenium, and precious metals include silver and gold. In one embodiment, the one or more included platinum group or refractory metals substitute at least partially for nickel, such that the alloy exhibits reduced nickel content, or is substantially nickel free. The stents exhibit improved radiopacity as compared to similar alloys including greater amounts of nickel.

Radiopaque intraluminal stents comprising cobalt-based alloys containing one or more platinum group metals, refractory metals, or combinations thereof

Bioabsorbable polymeric stent patterns with linking struts between rings that are designed to fail upon deployment of the stent are disclosed.

Bioabsorbable superficial femoral stent patterns with designed to break links

Methods are disclosed including thermally processing a scaffold to increase the radial strength of the scaffold when the scaffold is deployed from a crimped state to a deployed state such as a nominal deployment diameter. The thermal processing may further maintain or increase the expansion capability of the scaffold when expanded beyond the nominal diameter.

Thermal processing of polymer scaffolds

A systems and method for reducing coating defects on a stent may involve a support apparatus comprising wire cage for carrying a stent. The support apparatus may have no structure that extends inside the stent. A support apparatus may include a plurality of wires that pass through the stent but do not pass through the midplane of the stent. A support apparatus may contact only the proximal ends of the stent. The method may involve keeping the stent in motion during a spray coating process to prevent the stent from having a point remain in continuous contact with a support apparatus.

System for coating a stent

Methods and systems for controlling the moisture content of biodegradable and bioresorbable polymer resin during extrusion above a lower limit that allows for plasticization of the polymer resin melt and below an upper limit to reduce or prevent molecular weight loss are disclosed. Methods are further disclosed involving plasticization of a polymer resin for feeding into an extruder with carbon dioxide and freon.

Controlling moisture in and plasticization of bioresorbable polymer for melt processing

A method of loading a composition into a structural element of a stent, where the structural element is defined by a lumen and at least one opening to access the lumen. The composition may comprise a therapeutic agent, and wherein at a temperature of 30&#xb0; C. and at one atmosphere, the composition may be in a solid state or semi-solid state.

Methods of loading a hollow stent with a drug or drug formulation

An implantable sent comprises a radiopaque marker that provides a structural connection between two parts made of a polymer substrate material. The two parts can be one bending element of one radially expandable ring and another bending element of an adjacent expandable ring. The two parts can be two bending elements of the same radially expandable ring. The radiopaque marker can be in the form of an entire radially expandable ring.

Polymeric stent with structural radiopaque marker

The present invention provides an absorbable coating for an implantable device and the methods of making and using the same.

Absorbable coating for implantable device

A scaffold is formed by several segments joined or connected to each other by only at least one coupling. The coupling decouples the segments in the axial direction over a finite distance of axial displacement. The scaffold when implanted in a peripheral vessel reduces loading on rings of a segment due to the decoupling of the segments in the axial direction over the finite distance.

Coupled scaffold segments

A scaffold includes a radiopaque marker connected to a strut. The marker is retained within the strut by one or more of a mechanical interference fit, a polymer coating or melt, and/or by friction. The marker can take the form of a bead, rivet or snap-in marker, or a tube deformed when attached to the strut. The strut is made from a tube. The strut has a thickness of about 100 microns.

Scaffolds having radiopaque markers

An implantable stent includes a plurality of rings. At least a distal end ring has an eased corner feature formed in the polymer substrate at a radially outward, distal-facing corner of the ring while relatively sharp corners of the polymer substrate are maintained in radially inward corners of the ring.

Stent with eased corner feature

A method for crimping a stent with a polymer coating in a humid environment is disclosed.

Crimping method

Growing community of inventors

San Jose, CA, United States of America

Stephen D Pacetti