Alexza Pharmaceuticals, Inc.

Stephen D Cross

Martin J Wensley

Curtis Peter Tom

Daniel J Myers

Joshua D Rabinowitz

Ron L Hale

Reynaldo J Quintana

Peter Lloyd

Craig C Hodges

Ryan Timmons

Mathieu Herbette

Andrew J G Kelly

William W Shen

Justin M Virgili

Devices and methods of entraining a substance within an airflow are disclosed. Condensation aerosol delivery devices and methods of consistently producing multiple doses of a substance, such as a drug, having high purity, high yield, characterized by a particle size distribution appropriate for pulmonary delivery, and which can be administered to a user in a single dose are also disclosed.

Multiple dose condensation aerosol devices and methods of forming condensation aerosols

A device for delivering a drug by inhalation is disclosed. The device includes a body defining an interior flow-through chamber having upstream and downstream chamber openings, and a drug supply unit contained within the chamber for producing, upon actuation, a heated drug vapor in a condensation region of the chamber. Gas drawn through the chamber region at a selected gas-flow rate is effective to form drug condensation particles from the drug vapor having a selected MMAD between 0.02 and 0.1 MMAD or between 1 and 3.5 &#x3bc;m. A gas-flow control valve disposed upstream of the unit functions to limit gas-flow rate through the condensation region to the selected gas-flow rate. An actuation switch in the device activates the drug-supply unit, such that the drug-supply unit can be controlled to produce vapor when the gas-flow rate through the chamber is at the selected flow rate.

Inhalation device for producing a drug aerosol

Growing community of inventors

Alamo, CA, United States of America

Stephen D Cross