3m Innovative Properties Company

Solventum Intellectual Properties Company

Exxonmobil Chemical Patents Inc.

Exxon Chemical Patents, Inc.

Stephen B Roscoe

Babu Nana Gaddam

Kevin Michael Lewandowski

George W Griesgraber

Duane Douglas Fansler

Stephanie J Moeller

Larry R Krepski

Steven M Heilmann

Michael S Wendland

John L Battiste

Jesse D Miller

Bryan T Whiting

Kurt J Halverson

Neal A Rakow

Kenton D Budd

Jason W Bjork

Serkan Yurt

Chikafumi Yokoyama

John E Bailey

Jerald K Rasmussen

Hae-Seung Harry Lee

Anthony Jay Dias

Toshihiro Kasai

Phillip Angelo Bolea

Yi He

Manjiri T Kshirsagar

Stefan H Gryska

Richard B Ross

John F Walzer, Jr

Myungchan Kang

Jitendra Singh Rathore

Joon Chatterjee

Evan D Brutinel

Cynthia D Zook

Tonya D Bonilla

Minghua Dai

Shih-Hung Chou

Eric R Jackson

Hsi-Chou Liu

Lester H McIntosh, Iii

Renee K Cline

Matthew H Frey

Jayshree Seth

Ahmed Salih Abuelyaman

Jean M Frechet

Rajdeep S Kalgutkar

Jean M J Frechet

Janet A Venne

Paul J Homnick

Radoslav Atanasoski

Haeen Sykora

Payam Khodaparast

Charles J Studiner, Iii

Michael J Svarovsky

Daniel J O'Neal

John H Thomas, Iii

Aaron T Hedegaard

Deepti Gopalakrishnan

Michael L Husberg

Eli Narveson

Philip A Bolea

Toshihro Kasai

Eli P Narveson

Daniel J O'neal

A self-contained biological sterilization indicator comprises: a housing; bacterial spores comprising, and/or capable of producing, an enzyme capable of catalyzing cleavage of an enzyme substrate; and a frangible container containing a composition, wherein the composition comprises the enzyme substrate, wherein if the frangible container is broken the composition will contact the bacterial spores to form a mixture having an initial pH in the range from 6.0 to 9.0. The enzyme substrate comprises a fluorinated 4′-alkylumbelliferyl α-D-glucopyranoside represented by the structural formula (I), wherein R is an alkyl group having from 1 to 12 carbon atoms. A biological sterilization indicator comprising a kit containing isolated components comprising (i) bacterial spores comprising, and/or capable of producing, an enzyme capable of catalyzing cleavage of the enzyme substrate and a method of assessing efficacy of a sterilization process are also disclosed.

8-fluoro-4-alkylumbelliferyl α-D-glucopyranoside, biological sterilization indicator including the same and its use in a method of determining efficacy of a sterilization process

A self-contained biological sterilization indicator comprises: a housing; bacterial spores comprising, and/or capable of producing, an enzyme capable of catalyzing cleavage of an enzyme substrate; and a frangible container containing a composition, wherein the composition comprises the enzyme substrate, wherein if the frangible container is broken the composition will contact the bacterial spores to form a mixture having an initial pH in the range from 6.0 to 9.0. The enzyme substrate comprises a fluorinated 4'-alkylumbelliferyl α-D-glucopyranoside represented by the structural formula (I) wherein one of Rand Ris F and the other is H, and Ris an alkyl group having from 1 to 12 carbon atoms. A biological sterilization indicator comprising a kit containing isolated components comprising (i) bacterial spores comprising, and/or capable of producing, an enzyme capable of catalyzing cleavage of the enzyme substrate and a method of assessing efficacy of a sterilization process are also disclosed.

Fluorinated 4'-alkylumbelliferyl a-D-glucopyranosides, biological sterilization indicators including the same and methods of using the same

Articles with covalently attached thiocarbonylthio-containing groups are provided. More specifically, the articles include a solid polymeric substrate with a plurality of thiocarbonylthio-containing groups covalently attached directly to a carbon atom in a polymeric backbone of the solid polymeric substrate. Methods of making the articles with covalently attached thiocarbonylthio-containing are provided. Additionally, methods of using these articles to generate further articles with covalently attached polymeric chains are provided.

Polymeric substrates with attached polymeric chains

A polymerizable compound is represented by the formula (I). Each Rindependently represents a monovalent group having from 3 to 12 carbon atoms that comprises at least one of an epoxy group, an acryl group, or a methacryl group. Each Rindependently represents H, F, Cl, Br, C-Calkyl, C-Ccarbonylalkyl, or C-Ccarboalkoxy. Each Rindependently represents H, F, Cl, Br, C-Calkyl, C-Ccarbonylalkyl, or C-Ccarboalkoxy. Each n is independently 0, 1, 2, 3, or 4. Curable compositions including the polymerizable compound are also disclosed.

Polymerizable 4,4'-spirobi[chromane]-2,2′-diones and curable compositions including the same

Controlled radical initiators, reaction mixtures containing the controlled radical initiators and various ethylenically unsaturated monomers, polymeric materials formed from the reaction mixtures, crosslinkable compositions containing the polymeric materials, crosslinked compositions formed from the crosslinkable compositions, and articles containing the polymeric materials, the crosslinkable compositions, or the crosslinked compositions are provided. The controlled radical initiators are bis-dithiocarbamate or bis-dithiocarbonate compounds having a single carbon between the two dithiocarbamate or dithiocarbonate groups. Also attached to that single carbon is a ketone group.

Polymeric materials formed using initiators with two thiocarbonylthio-containing groups

First articles with covalently attached thiocarbonylthio-containing groups are provided. More specifically, the first articles are a functionalized substrate that contains a solid polymeric substrate with a plurality of thiocarbonylthio-containing groups covalently attached directly to carbon atoms in a polymeric backbone of the solid polymeric substrate. Methods of making the first articles with covalently attached thiocarbonylthio-containing groups are provided. Additionally, second articles and methods of using the first articles to generate second articles with covalently attached polymeric chains are provided.

Polymeric substrates with attached thiocarbonylthio-containing groups

Controlled radical initiators, reaction mixtures containing the controlled radical initiators and various ethylenically unsaturated monomers, polymeric materials formed from the reaction mixtures, crosslinkable compositions containing the polymeric materials, crosslinked compositions formed from the crosslinkable compositions, and various articles are provided. The controlled radical initiators are bis-dithiocarbamate or bis-dithiocarbonate compounds having a carbonyl group between the two dithiocarbamate or dithiocarbonate groups.

Polymeric materials formed using initiators with a ketone group and two thiocarbonylthio-containing groups

Controlled radical initiators that are ketone-containing dithiocarbamate or ketone-containing dithiocarbonate compounds are used to form polymeric materials that have a single polymeric block or multiple polymeric blocks. Reaction mixtures containing controlled radical initiators and various ethylenically unsaturated monomers, polymeric materials formed from the reaction mixtures, crosslinkable compositions containing the polymeric materials, crosslinked compositions formed from the crosslinkable compositions, and articles containing the polymeric materials, the crosslinkable compositions, or the crosslinked compositions are provided.

Ketone-containing controlled radical initiators for polymerization reactions

Crosslinkable polymeric materials, crosslinked polymeric materials, articles containing the crosslinkable polymeric materials or crosslinked polymeric materials, and methods of making the articles and various compositions are provided. More particularly, the crosslinkable composition contains a) a first polymeric material, which has terminal dithiocarbamate or dithiocarbonate groups, b) a crosslinking composition containing a chlorinated triazine crosslinking agent and/or a crosslinking monomer having two or more ethylenically unsaturated groups, and c) a thixotropic agent containing metal oxide particles. The crosslinkable composition may be printable or dispensed. In some embodiments, the crosslinked composition is a pressure-sensitive adhesive.

Polymeric compositions prepared with a controlled radical initiator

Silicone-based elastomeric materials, articles containing the silicone-based elastomeric materials, reaction mixtures used to form the silicone-based elastomeric materials, and methods of making the silicone-based elastomeric materials are described. The silicone-based elastomeric materials are prepared by polymerizing silicone compounds having at least two ethylenically unsaturated groups in the presence of actinic radiation and a controlled radical initiator. The controlled radical initiators are bis-dithiocarbamate or bis-dithiocarbonate compounds having a single carbon between the two dithiocarbamate or dithiocarbonate groups. The silicone-based elastomeric materials typically have improved mechanical properties compared to silicone-based elastomeric materials formed by free radical polymerization reactions in the presence of conventional photoinitiators.

Photo-radical cure of silicones

Silicone-based pressure-sensitive adhesives, reaction mixtures used to form the pressure-sensitive adhesives, methods of making the silicone-based pressure-sensitive adhesives, and articles containing the silicone-based pressure-sensitive adhesives are described. More particularly, the silicone-based pressure-sensitive adhesives include silicone-based elastomeric materials that are prepared by polymerizing a silicone compound having at least two ethylenically unsaturated groups in the presence of actinic radiation (e.g., ultraviolet radiation) and a controlled radical initiator. The controlled radical initiator is a bis-dithiocarbamate or bis-dithiocarbonate compound having a single carbon between the two dithiocarbamate or dithiocarbonate groups.

Silicone-based pressure-sensitive adhesive

Crosslinkable compositions are provided that contain a) a polymeric material having at least two terminal dithiocarbamate groups or two terminal dithiocarbonate groups and b) a monomer composition that includes at least a crosslinking monomer having two or more ethylenically unsaturated groups. The polymeric materials in the crosslinkable compositions undergo chain extension and crosslinking reactions when exposed to actinic radiation in the ultraviolet region of the electromagnetic spectrum. Additionally, crosslinked compositions, articles that contain the crosslinkable compositions or the crosslinked compositions, and methods of making the articles are provided.

Crosslinkable and crosslinked polymeric materials

Controlled radical initiators, reaction mixtures containing the controlled radical initiators and various ethylenically unsaturated monomers, polymeric materials formed from the reaction mixtures, crosslinkable compositions containing the polymeric materials, and crosslinked compositions formed from the crosslinkable compositions are provided. The controlled radical initiators are bis-dithiocarbamate or bis-dithiocarbonate compounds having a single carbon between the two dithiocarbamate or dithiocarbonate groups.

Polymeric materials formed using controlled radical initiators

Assay devices are provided including a receptacle having a sample entry port; a plunger disposed within the receptacle; at least one reagent; a membrane attached to a first surface of the plunger; a wick providing capillary force; and a detection zone. The membrane includes a target conjugate zone in which affinity components are disposed. Capture compounds are immobilized in a detection zone, which is located between the target conjugate zone and the wick. A method of detecting a target analyte is also provided, including providing the assay device; providing a sample suspected to contain a target analyte; adding the sample onto the device; allowing the sample to travel along the membrane until the sample reaches the detection zone; immobilizing the target analyte through reaction of the target analyte with the capture compounds; reacting the immobilized target analyte with a reagent to generate a detectable signal; and detecting the generated signal.

Assay devices and method of detecting a target analyte

Controlled radical initiators, reaction mixtures containing the controlled radical initiators and various ethylenically unsaturated monomers, and polymeric materials formed from the reaction mixtures are provided. The controlled radical initiators are bis-dithiocarbamate or bis-dithiocarbonate compounds with a single carbon atom between the two dithiocarbamate or dithiocarbonate groups. Polymeric materials such as homopolymers, random copolymers, and block copolymers can be prepared using the controlled radical initiators.

Polymeric material and methods of making using controlled radical initiators

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Woodbury, MN, United States of America

Stephen B Roscoe